Department of Rehabilitation Science and Health Technology, Oslo Metropolitan University, Oslo, Norway.
Department of Rehabilitation Science and Health Technology, Centre for Intelligent Musculoskeletal Health, Oslo Metropolitan University, Oslo, Norway.
PLoS One. 2022 Dec 29;17(12):e0278906. doi: 10.1371/journal.pone.0278906. eCollection 2022.
There is limited knowledge on the association between different health complaints and the development of persistent musculoskeletal pain in adolescents. The aims of this study were to assess whether specific health complaints, and an accumulation of health complaints, in the first year of upper-secondary school, were associated with persistent musculoskeletal pain 2 years later. We used data from a population-based cohort study (the Fit Futures Study in Norway), including 551 adolescents without persistent musculoskeletal pain at baseline. The outcome was persistent musculoskeletal pain (≥3 months) 2 years after inclusion. The following self-reported health complaints were investigated as individual exposures at baseline: asthma, allergic rhinitis, atopic eczema, headache, abdominal pain and psychological distress. We also investigated the association between the accumulated number of self-reported health complaints and persistent musculoskeletal pain 2 years later. Logistic regression analyses estimated adjusted odds ratios (ORs) with 95% confidence intervals (CIs). At the 2-year follow-up, 13.8% (95% CI [11.2-16.9]) reported persistent musculoskeletal pain. Baseline abdominal pain was associated with persistent musculoskeletal pain 2 years later (OR 2.33, 95% CI [1.29-4.19], p = 0.01). Our analyses showed no statistically significant associations between asthma, allergic rhinitis, atopic eczema, headache or psychological distress and persistent musculoskeletal pain at the 2-year follow-up. For the accumulated number of health complaints, a higher odds of persistent musculoskeletal pain at the 2-year follow-up was observed for each additional health complaint at baseline (OR 1.33, 95% CI [1.07-1.66], p = 0.01). Health care providers might need to take preventive actions in adolescents with abdominal pain and in adolescents with an accumulation of health complaints to prevent development of persistent musculoskeletal pain. The potential multimorbidity perspective of adolescent musculoskeletal pain is an important topic for future research to understand the underlying patterns of persistent pain conditions in adolescents.
关于不同健康问题与青少年持续性肌肉骨骼疼痛发展之间的关联，我们的了解有限。本研究旨在评估高中第一年是否存在特定的健康问题和健康问题的积累与两年后持续性肌肉骨骼疼痛相关。我们使用了一项基于人群的队列研究（挪威 Fit Futures 研究）的数据，该研究纳入了 551 名基线时无持续性肌肉骨骼疼痛的青少年。该研究的结局是纳入后两年是否存在持续性肌肉骨骼疼痛（≥3 个月）。在基线时，我们将以下自我报告的健康问题作为个体暴露进行调查：哮喘、过敏性鼻炎、特应性皮炎、头痛、腹痛和心理困扰。我们还调查了自我报告的健康问题数量的累积与两年后持续性肌肉骨骼疼痛之间的关联。逻辑回归分析估计了调整后的比值比（OR）及其 95%置信区间（CI）。在两年的随访中，13.8%（95%CI[11.2-16.9]）报告存在持续性肌肉骨骼疼痛。基线时的腹痛与两年后的持续性肌肉骨骼疼痛相关（OR 2.33，95%CI[1.29-4.19]，p=0.01）。我们的分析显示，在两年的随访中，哮喘、过敏性鼻炎、特应性皮炎、头痛或心理困扰与持续性肌肉骨骼疼痛之间无统计学显著关联。对于健康问题的累积数量，与基线时存在的每个额外健康问题相比，两年后持续性肌肉骨骼疼痛的可能性更高（OR 1.33，95%CI[1.07-1.66]，p=0.01）。医疗保健提供者可能需要在出现腹痛的青少年和健康问题累积的青少年中采取预防措施，以预防持续性肌肉骨骼疼痛的发生。青少年肌肉骨骼疼痛的潜在多种疾病模式是未来研究的一个重要课题，以了解青少年持续性疼痛状况的潜在模式。
