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飞秒激光辅助囊切开术后人工晶状体前边缘设计对前囊形态变化的影响。

Effects of intraocular lens anterior edge design on anterior capsule morphology changes following femtosecond laser-assisted capsulotomy.

机构信息

Clinical College of Ophthalmology, Tianjin Medical University, Tianjin, China.

Tianjin Key Laboratory of Ophthalmology and Visual Science, Tianjin Eye Institute, Tianjin Eye Hospital, Tianjin, China.

出版信息

BMC Ophthalmol. 2022 Dec 29;22(1):515. doi: 10.1186/s12886-022-02751-x.

DOI:10.1186/s12886-022-02751-x
PMID:36581925
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9801536/
Abstract

PURPOSE

To compare morphological changes in the anterior capsule of two intraocular lenses (IOLs) with different anterior edge designs 6 months after femtosecond laser-assisted capsulotomy surgery (FLACs).

METHODS

This study included 168 eyes from168 patients undergoing FLACs. Group A included 74 eyes from 74 patients who had an Acrysof IQ Restor SN6AD3 IOL implantation with a flat anterior edge and Group B included 94 eyes of 94 patients with a TECNIS Multifocal ZMB00 IOL implantation and a "peak-like" anterior edge. All patients were followed up for 6 months. We assessed anterior capsule morphological changes including variation of anterior opening diameters and lens epithelial cell (LEC) proliferation in four directions, variation of anterior opening area, and the level of anterior capsule opacification (ACO).

RESULTS

Variation of anterior opening diameters in 4 directions were significantly lower in Group B (P < 0.05). Obvious shrinkage ratio of anterior opening diameters and contraction of anterior opening area (P < 0.05) appeared in Group A. LEC proliferation was along the "peak" in Group B, while it spread to the edge of anterior capsule in Group A. ACO grades 6 months after operation in Groups A and B were as follows: grade I in 28.38% and 82.98% of eyes, grade II in 51.35% and 17.02% of eyes, and grade III in 20.27% and 0% of eyes, respectively.

CONCLUSIONS

These findings suggest that a "peak-like" IOL anterior edge design played an important role in maintaining the morphology of anterior capsule in the early postoperative stage.

摘要

目的

比较飞秒激光辅助囊膜切开术后 6 个月两种不同边缘设计的人工晶状体（IOL）前囊形态变化。

方法

本研究纳入 168 例（168 只眼）接受飞秒激光辅助囊膜切开术的患者。A 组 74 例（74 只眼）植入 Acrysof IQ Restor SN6AD3 IOL，前边缘平坦；B 组 94 例（94 只眼）植入 TECNIS Multifocal ZMB00 IOL，前边缘呈“峰样”。所有患者均随访 6 个月。评估前囊形态变化，包括前开口直径在 4 个方向的变化和 Lens epithelial cell（LEC）增殖，前开口面积的变化，以及前囊混浊（ACO）程度。

结果

B 组前开口直径在 4 个方向的变化明显低于 A 组（P < 0.05）。A 组前开口直径明显缩小，前开口面积收缩（P < 0.05）。B 组 LEC 增殖呈“峰样”，而 A 组则向前囊边缘扩散。术后 6 个月 A、B 两组 ACO 分级如下：Ⅰ级分别为 28.38%和 82.98%；Ⅱ级分别为 51.35%和 17.02%；Ⅲ级分别为 20.27%和 0%。

结论

这些发现表明，“峰样”IOL 前边缘设计在术后早期对维持前囊形态起重要作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0c6/9801536/34dcaf43a1d3/12886_2022_2751_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0c6/9801536/9d5177458796/12886_2022_2751_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0c6/9801536/bccdf17fd7ba/12886_2022_2751_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0c6/9801536/e96d7d7890d3/12886_2022_2751_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0c6/9801536/b64f2d04c392/12886_2022_2751_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0c6/9801536/34dcaf43a1d3/12886_2022_2751_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0c6/9801536/9d5177458796/12886_2022_2751_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0c6/9801536/bccdf17fd7ba/12886_2022_2751_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0c6/9801536/e96d7d7890d3/12886_2022_2751_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0c6/9801536/b64f2d04c392/12886_2022_2751_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d0c6/9801536/34dcaf43a1d3/12886_2022_2751_Fig5_HTML.jpg

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