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妊娠期再激活播散性肺结核:病例报告及文献复习

Reactivated disseminated tuberculosis in pregnancy: Case report and review of the literature.

作者信息

Beshar Isabel, Moon Ashley S, Pendse Ruchita, Nevins Andrew B, Litkouhi Babak

机构信息

Department of Obstetrics & Gynecology, Stanford University, Stanford, CA, USA.

Divison of Gynecologic Oncology, Department of Obstetrics & Gynecology, Stanford University, Stanford, CA, USA.

出版信息

Case Rep Womens Health. 2022 Dec 14;37:e00475. doi: 10.1016/j.crwh.2022.e00475. eCollection 2023 Mar.

DOI:10.1016/j.crwh.2022.e00475
PMID:36582263
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9792344/
Abstract

This case report describes the evaluation and management of a 32-year-old woman who presented shortly after a fetal demise at 23 weeks of gestation with multiple symptoms, including bloody vaginal discharge. Although the initial diagnostic concern was for metastatic malignancy, the patient was ultimately determined to have disseminated tuberculosis. Genital tuberculosis is common worldwide, yet guidelines for evaluation are limited. This report highlights the relationship between pregnancy-reactivated tuberculosis, and guides clinicians on diagnostic and management considerations in the peripartum period.

摘要

本病例报告描述了一名32岁女性的评估与管理情况。该女性在妊娠23周时胎儿死亡后不久出现多种症状,包括阴道血性分泌物。尽管最初的诊断关注点是转移性恶性肿瘤,但患者最终被确诊为播散性结核病。生殖器结核在全球范围内都很常见,但评估指南有限。本报告强调了妊娠再激活型结核病之间的关系,并为临床医生在围产期的诊断和管理考量提供指导。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d29/9792344/b58af01788f7/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d29/9792344/7ad1097a0f1d/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d29/9792344/fce14148addd/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d29/9792344/b58af01788f7/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d29/9792344/7ad1097a0f1d/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d29/9792344/fce14148addd/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d29/9792344/b58af01788f7/gr3.jpg

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本文引用的文献

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Acute miliary tuberculosis in pregnancy after in vitro fertilization and embryo transfer: a report of seven cases.体外受精-胚胎移植术后妊娠合并急性血行播散性肺结核 7 例报告
BMC Infect Dis. 2021 Sep 6;21(1):913. doi: 10.1186/s12879-021-06564-z.
2
An Unfortunate Case of Reactivation of Tuberculosis in a Postpartum Female.一名产后女性结核病复发的不幸病例。
Cureus. 2020 Nov 29;12(11):e11775. doi: 10.7759/cureus.11775.
3
A case report of cervical pregnancy after fertilization complicated by tuberculosis and a literature review.
1例受精后宫颈妊娠合并结核的病例报告及文献复习
Open Med (Wars). 2020 Nov 9;15(1):1083-1086. doi: 10.1515/med-2020-0236. eCollection 2020.
4
Pregnancy in a patient with endometrial tuberculosis by in vitro fertilization: a case report.子宫内膜结核患者通过体外受精成功妊娠:一例病例报告
J Int Med Res. 2020 Nov;48(11):300060520967824. doi: 10.1177/0300060520967824.
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Maternal Immunological Adaptation During Normal Pregnancy.正常妊娠期间的母体免疫适应性。
Front Immunol. 2020 Oct 7;11:575197. doi: 10.3389/fimmu.2020.575197. eCollection 2020.
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Peritoneal tuberculosis: the great mimicker.腹膜结核:极具伪装性的疾病。
Int J Gynecol Cancer. 2020 Apr;30(4):546-550. doi: 10.1136/ijgc-2020-001291. Epub 2020 Mar 9.
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Increased risk of active tuberculosis during pregnancy and postpartum: a register-based cohort study in Sweden.孕期及产后活动性肺结核风险增加:瑞典一项基于登记的队列研究
Eur Respir J. 2020 Mar 20;55(3). doi: 10.1183/13993003.01886-2019. Print 2020 Mar.
8
Detection of Mycobacterium tuberculosis in AFB smear-negative sputum specimens through MTB culture and GeneXpert MTB/RIF assay.通过 MTB 培养和 GeneXpert MTB/RIF 检测对 AFB 涂片阴性痰标本中结核分枝杆菌的检测。
Int J Immunopathol Pharmacol. 2019 Jan-Dec;33:2058738419827174. doi: 10.1177/2058738419827174.
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Clin Infect Dis. 2019 Mar 5;68(6):e1-e47. doi: 10.1093/cid/ciy866.
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