Lin Zu-Jin, Mahammed Shaheer A R, Liu Tian-Fu, Cao Rong
State Key Laboratory of Structural Chemistry, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou 350002, P. R. China.
College of Life Science, Fujian Agriculture and Forestry University, Fuzhou, Fujian 350002, P. R. China.
ACS Cent Sci. 2022 Dec 28;8(12):1589-1608. doi: 10.1021/acscentsci.2c01196. Epub 2022 Dec 16.
Hydrogen-bonded organic frameworks (HOFs), self-assembled from organic or metalated organic building blocks (also termed as tectons) by hydrogen bonding, π-π stacking, and other intermolecular interactions, have become an emerging class of multifunctional porous materials. So far, a library of HOFs with high porosity has been synthesized based on versatile tectons and supramolecular synthons. Benefiting from the flexibility and reversibility of H-bonds, HOFs feature high structural flexibility, mild synthetic reaction, excellent solution processability, facile healing, easy regeneration, and good recyclability. However, the flexible and reversible nature of H-bonds makes most HOFs suffer from poor structural designability and low framework stability. In this Outlook, we first describe the development and structural features of HOFs and summarize the design principles of HOFs and strategies to enhance their stability. Second, we highlight the state-of-the-art development of HOFs for diverse applications, including gas storage and separation, heterogeneous catalysis, biological applications, sensing, proton conduction, and other applications. Finally, current challenges and future perspectives are discussed.
氢键有机框架（HOFs）是由有机或金属化有机构筑单元（也称为构造子）通过氢键、π-π堆积和其他分子间相互作用自组装而成的，已成为一类新兴的多功能多孔材料。到目前为止，基于多种构造子和超分子合成子，已经合成了一系列具有高孔隙率的HOFs。受益于氢键的灵活性和可逆性，HOFs具有高结构灵活性、温和的合成反应、优异的溶液加工性、易于修复、易于再生和良好的可回收性。然而，氢键的灵活和可逆性质使得大多数HOFs存在结构设计性差和框架稳定性低的问题。在这篇展望中，我们首先描述HOFs的发展和结构特征，并总结HOFs的设计原则以及提高其稳定性的策略。其次，我们重点介绍HOFs在多种应用中的最新进展，包括气体存储与分离、多相催化、生物应用、传感、质子传导及其他应用。最后，讨论了当前面临的挑战和未来的前景。
