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钕钇铝石榴石激光在气管肿瘤治疗中的作用。

Role of the neodymium YAG laser in the management of tracheal tumours.

作者信息

George P J, Garrett C P, Hetzel M R

机构信息

National Medical Laser Centre, University College Hospital, London.

出版信息

Thorax. 1987 Jun;42(6):440-4. doi: 10.1136/thx.42.6.440.

Abstract

Twenty one patients with tracheal tumours (10 primary and 11 secondary) have been treated with the neodymium YAG laser under general anaesthesia. Fourteen of these patients presented with impending asphyxia and in 11 cases this was dramatically relieved with emergency laser treatment. The improvements in peak expiratory flow (PEF) ranged from 26% to 512%. The three patients who did not respond were immediately given other treatments but died in hospital. The remaining seven patients were not in severe respiratory distress and were treated electively; all were thought to have benefited from their treatment, the mean increase in PEF being 36%. The improvement obtained in the 11 patients who responded to emergency laser treatment provided time in which to assess the disease carefully and plan the most appropriate longer term management with surgery, radiotherapy, tracheal stenting, or repeat laser treatment. The patients who were treated electively have either not required further treatment of have been managed with repeat laser treatments alone. Laser treatment provides an excellent method of resuscitating patients with life threatening tracheal obstruction and enables subsequent management to be carefully planned. In some cases this longer term management should be with further laser treatment alone.

摘要

21例气管肿瘤患者(10例原发性,11例继发性)在全身麻醉下接受了钕钇铝石榴石激光治疗。其中14例患者出现窒息先兆,11例经紧急激光治疗后窒息症状明显缓解。呼气峰值流速(PEF)的改善幅度在26%至512%之间。3例无反应的患者立即接受了其他治疗,但均在医院死亡。其余7例患者无严重呼吸窘迫,接受了择期治疗;所有患者均认为从治疗中获益,PEF平均增加36%。对紧急激光治疗有反应的11例患者所获得的改善,为仔细评估病情并制定最适当的长期治疗方案(手术、放疗、气管支架置入或重复激光治疗)提供了时间。接受择期治疗的患者要么无需进一步治疗,要么仅接受了重复激光治疗。激光治疗为抢救有生命危险的气管阻塞患者提供了一种极好的方法,并能使后续治疗得到精心规划。在某些情况下,这种长期治疗应仅采用进一步的激光治疗。

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