Petrou M, Kaplan D, Goldstraw P
Department of Thoracic Surgery, Royal Brompton National Heart and Lung Hospital, London.
Thorax. 1993 Nov;48(11):1156-9. doi: 10.1136/thx.48.11.1156.
Major airways obstruction is a distressing cause of morbidity and mortality. For disease that is extensive and recurrent, there is a need for a safe and cost effective technique for palliation.
The results of 29 patients with tracheobronchial obstruction (24 malignant and five benign) treated by diathermy resection alone or in combination with endobronchial stenting have been reviewed.
The major site of obstruction was the trachea in 14, main carina in seven, right main bronchus in six, and left main bronchus in two patients. Fifteen had received other forms of treatment beforehand including external radiotherapy, endoscopic dilatation, and laser resection (Nd:YAG). Five patients required two or more treatment sessions for symptom recurrence. Ten patients also received additional treatment with a stent (nine) or insertion of gold grains (one). There were no intraoperative deaths or complications and the average length of stay was five days (range 2-14). Twenty eight patients reported immediate symptomatic relief, and objective improvement in the results of lung function tests was seen in eight patients whose condition was less acute and where preoperative lung function tests could be undertaken (average improvement in FEV1 of 53.1% and in FVC of 20.6%).
Bronchoscopic diathermy resection is an effective and safe method for relieving the symptoms of tracheobronchial obstruction at appreciably less cost than laser resection.
大气道阻塞是导致发病和死亡的令人痛苦的原因。对于广泛且复发性的疾病,需要一种安全且具有成本效益的姑息治疗技术。
回顾了29例气管支气管阻塞患者(24例恶性和5例良性)单独采用透热切除术或联合支气管内支架置入术的治疗结果。
阻塞的主要部位为气管14例,主隆突7例,右主支气管6例,左主支气管2例。15例患者此前接受过其他形式的治疗,包括体外放疗、内镜扩张和激光切除术(钕:钇铝石榴石)。5例患者因症状复发需要接受两次或更多次治疗。10例患者还接受了额外的治疗,其中9例置入支架,1例植入金粒。无术中死亡或并发症,平均住院时间为5天(范围2 - 14天)。28例患者报告症状立即缓解,8例病情不太危急且术前可进行肺功能测试的患者肺功能测试结果有客观改善(第一秒用力呼气容积平均改善53.1%,用力肺活量平均改善20.6%)。
支气管镜透热切除术是一种有效且安全的方法,可缓解气管支气管阻塞症状,成本明显低于激光切除术。