Department of Rheumatology and Immunology, The Affiliated Hospital of Southwest Medical University, No. 25,Taiping Street, Jiangyang District, Luzhou, 646000, Sichuan Province, People's Republic of China.
Department of Ophthalmology, The Affiliated Hospital of Southwest Medical University, No. 25, Taiping Street, Jiangyang District, Luzhou, 646000, Sichuan Province, People's Republic of China.
Clin Rheumatol. 2023 May;42(5):1285-1295. doi: 10.1007/s10067-022-06485-5. Epub 2023 Jan 5.
Antiphospholipid syndrome is an autoimmune disorder characterized by recurrent vascular thrombosis and pregnancy losses in the presence of persistently positive antiphospholipid antibodies. Bibliometric analysis and altmetric analysis are methods of analyzing academic productivity and influence. Currently, the assessment of antiphospholipid syndrome through the above analyses is lacking. This study investigated the quantity and quality of studies in the field of antiphospholipid syndrome and revealed the characteristics of worldwide productivity on this disease by the bibliometric analysis and altmetric analysis.
The terms "APS," "antiphospholipid syndrome," "antiphospholipid-antibody syndrome," and "Hughes syndrome" were searched on the Web of Science Core Collection from January 1, 2011, to December 31, 2021. Original articles and reviews were selected. We set the filters as "English."
A total of 1818 articles were retrieved from 68 countries, of which 20 met the criteria of major active countries. High-income countries contributed 1341 articles (73.48%). The number of articles annually increased significantly in the 10-year period (P < 0.001). The USA (253, 13.91%) was the most productive country. Adjusted by population, Serbia was top of the list. According to the gross domestic product analysis, Serbia ranked first. The most used keywords such as thrombosis and antiphospholipid antibodies were presented by keywords analyses. A content analysis found antithrombotic and anticoagulant therapy as research hotspots. A significant correlation was detected between average citations and altmetric attention scores (P = 0.002) and Mendeley readers count (P < 0.001). From 2011 to 2021, the number of global articles increased rapidly. Most papers came from high-income countries. The relationship between the bibliometric and altmetric analyses were basically consistent; therefore the two can prove/complement each other. Key points • We revealed the global productivity characteristics of the papers related to antiphospholipid syndrome by using the methods of bibliometric analysis and altmetric analysis. • We found the most selected articles that describe the treatment of antiphospholipid syndrome, especially antithrombotic and anticoagulant treatments, which may be the current research hotspot.
抗磷脂综合征是一种自身免疫性疾病，其特征是在持续存在抗磷脂抗体的情况下反复发生血管血栓形成和妊娠丢失。文献计量分析和 Altmetric 分析是分析学术产出和影响力的方法。目前，通过上述分析评估抗磷脂综合征的方法还很缺乏。本研究通过文献计量分析和 Altmetric 分析，调查了抗磷脂综合征领域的研究数量和质量，并揭示了全球对该病的生产力特征。
在 2011 年 1 月 1 日至 2021 年 12 月 31 日期间，在 Web of Science 核心合集上搜索了“APS”、“抗磷脂综合征”、“抗磷脂抗体综合征”和“Hughes 综合征”等术语。选择了原始文章和综述。我们设置了“英语”的过滤器。
从 68 个国家共检索到 1818 篇文章，其中 20 篇符合主要活跃国家的标准。高收入国家贡献了 1341 篇文章（73.48%）。在 10 年期间，文章数量呈显著增长趋势（P < 0.001）。美国（253 篇，13.91%）是最有生产力的国家。按人口调整后，塞尔维亚排名第一。根据国内生产总值分析，塞尔维亚排名第一。通过关键词分析呈现了血栓形成和抗磷脂抗体等最常用的关键词。内容分析发现抗血栓和抗凝治疗是研究热点。检测到平均引用量与 Altmetric 关注度得分（P = 0.002）和 Mendeley 读者计数（P < 0.001）之间存在显著相关性。2011 年至 2021 年，全球文章数量迅速增加。大多数论文来自高收入国家。文献计量分析和 Altmetric 分析的结果基本一致；因此，这两种方法可以相互证明或补充。关键点：• 我们通过文献计量分析和 Altmetric 分析的方法揭示了与抗磷脂综合征相关论文的全球生产力特征。• 我们发现了最常被选择的描述抗磷脂综合征治疗方法的文章，特别是抗血栓和抗凝治疗，这可能是当前的研究热点。
