Frontiera M, Myers A M
West J Med. 1987 Aug;147(2):157-60.
In reviewing the peripheral hematologic manifestations, bone marrow changes and clinical course in 41 consecutive patients with acquired immunodeficiency syndrome (AIDS), frequent findings included anemia (95%), leukopenia (76%), bone marrow hypercellularity (73%) and pancytopenia (41%). These hematologic abnormalities were not clearly associated with specific clinical manifestations of AIDS, but support the conclusion that the hematopoietic system is a target organ in AIDS. The mechanisms of these abnormalities still need to be evaluated. Clinicians should be aware of these commonly encountered changes.
在回顾41例连续获得性免疫缺陷综合征（AIDS）患者的外周血液学表现、骨髓变化及临床病程时，常见的表现包括贫血（95%）、白细胞减少（76%）、骨髓细胞增多（73%）和全血细胞减少（41%）。这些血液学异常与AIDS的特定临床表现并无明确关联，但支持造血系统是AIDS靶器官这一结论。这些异常的机制仍需评估。临床医生应知晓这些常见变化。
