Babu Reshma S, Lanjewar Ajay, Jadhav Ulhas, Wagh Pankaj, Aurangabadkar Gaurang, Upadhyay Puja
Department of Respiratory Medicine, Jawaharlal Nehru Medical College, Sawangi (Meghe), Wardha, Maharashtra, India.
J Family Med Prim Care. 2022 Oct;11(10):6581-6585. doi: 10.4103/jfmpc.jfmpc_263_22. Epub 2022 Oct 31.
The most common primary malignancies that affect the pericardium are lung cancers. Typically, pericardial involvement stays undiagnosed, with almost 1-20% of all tumor-related autopsies revealing invasion of the pericardium. Pericardial effusions are seldom the first location of metastasis and presentation of a primary malignancy. Malignant pericardial effusions are usually silent, although they cause dyspnea, chest discomfort, arrhythmias, cough, and, in rare cases, pericardial tamponade. In a patient with tamponade, a high index of tumor-related suspicion is crucial to rule out cancer. Emergency pericardiocentesis is indicated based on the clinical presentation, however, the patient frequently has a bad prognosis regardless of whether treatment is administered or not. In this case series, we report five cases of non-small cell lung cancer (NSCLC) with pericardial effusion as an initial presentation.
影响心包的最常见原发性恶性肿瘤是肺癌。通常，心包受累情况未被诊断出来，在所有与肿瘤相关的尸检中，几乎有1%至20%显示心包受到侵犯。心包积液很少是原发性恶性肿瘤转移和表现的首发部位。恶性心包积液通常没有症状，尽管它们会引起呼吸困难、胸部不适、心律失常、咳嗽，在极少数情况下还会导致心包填塞。对于有心包填塞的患者，高度怀疑与肿瘤相关对于排除癌症至关重要。根据临床表现需要进行紧急心包穿刺术，然而，无论是否进行治疗，患者的预后通常都很差。在本病例系列中，我们报告了5例以心包积液为首发表现的非小细胞肺癌（NSCLC）病例。
