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平价医疗法案对肾或肝移植后获得和结果的影响:移植登记研究。

Association of the Affordable Care Act on Access to and Outcomes After Kidney or Liver Transplant: A Transplant Registry Study.

机构信息

Department of Medicine, Duke University, Durham, North Carolina.

Department of Surgery, Duke University, Durham, North Carolina.

出版信息

Transplant Proc. 2023 Jan-Feb;55(1):56-65. doi: 10.1016/j.transproceed.2022.12.008. Epub 2023 Jan 7.

Abstract

BACKGROUND

To evaluate the effect of the Affordable Care Act (ACA) Medicaid expansion on payor mix among patients on the kidney and liver transplant waiting list as well as waiting list and post-transplant outcomes.

DESIGN

Using the Scientific Registry of Transplant Recipients, we performed a secondary data analysis of all patients on the kidney and liver transplant waiting list from 2007 to 2018. We described changes in payor mix by timing of state Medicaid expansion. We used competing risks models to estimate cause-specific hazard ratios for the effects of insurance and era on death/delisting and transplant. We used a Poisson regression model to estimate the effect of insurance and era on incidence rate ratio of inactivations on the waiting list. We used Cox proportional hazards models to estimate the effect of insurance and era on graft and patient survival.

RESULTS

A decade after implementation of the ACA, the prevalence of Medicaid beneficiaries listed for transplant increased by 2.5% (from 7.4% to 9.9%) for kidney and by 2.6% (15.3% to 17.9%) for liver. Expansion states had greater increases than nonexpansion states (kidney 3.8% vs 0.6%, liver 5.3% vs -1.8%). Among wait-listed patients, the magnitude of association of Medicaid insurance vs private insurance with transplant decreased over time for kidney candidates (era 1 subdistribution hazard ratio (SHR), 0.62 [95% CI, 0.60-0.64] vs era 3 SHR, 0.77 [95% CI, 0.74-0.70]) but increased for liver candidates (era 1 SHR, 0.85 [95% CI, 0.83-0.90] vs era 3 SHR 0.79 [95% CI, 0.77-0.82]). Medicaid-insured kidney and liver recipients had greater hazards of graft failure; this did not change over time (kidney: HR, 1.23 [95% CI, 1.06-1.44] liver: HR, 1.05 [95% CI, 0.94-1.17]).

CONCLUSIONS

For the millions of patients with chronic kidney and liver diseases, implementation of the ACA has resulted in only modest increases in access to transplant for the publicly insured vs the privately insured.

摘要

背景

评估平价医疗法案(ACA)医疗补助扩张对肾脏和肝脏移植候补患者的支付方构成以及候补和移植后结果的影响。

设计

利用器官移植受者科学注册处,我们对 2007 年至 2018 年所有肾脏和肝脏移植候补患者进行了二次数据分析。我们根据州医疗补助扩张的时间描述了支付方构成的变化。我们使用竞争风险模型来估计保险和时代对死亡/除名和移植的影响的特定原因危害比。我们使用泊松回归模型来估计保险和时代对候补名单上停用发生率的影响。我们使用 Cox 比例风险模型来估计保险和时代对移植物和患者生存的影响。

结果

ACA 实施十年后,接受肾脏移植的医疗补助受惠者的比例从 7.4%增加到 9.9%,肝脏从 15.3%增加到 17.9%。扩张州的增幅大于非扩张州(肾脏 3.8%比 0.6%,肝脏 5.3%比-1.8%)。在候补名单上的患者中,随着时间的推移, Medicaid 保险与私人保险与移植之间的关联程度对于肾脏候选者逐渐减弱(时代 1 亚分布危害比(SHR),0.62[95%置信区间,0.60-0.64]比时代 3 SHR,0.77[95%置信区间,0.74-0.70]),但对于肝脏候选者逐渐增强(时代 1 SHR,0.85[95%置信区间,0.83-0.90]比时代 3 SHR 0.79[95%置信区间,0.77-0.82])。接受 Medicaid 保险的肾脏和肝脏受者的移植物失败风险更高;随着时间的推移,这种情况并没有改变(肾脏:HR,1.23[95%置信区间,1.06-1.44];肝脏:HR,1.05[95%置信区间,0.94-1.17])。

结论

对于数百万患有慢性肾脏和肝脏疾病的患者来说,平价医疗法案的实施仅导致公共保险比私人保险更能获得移植的机会略有增加。

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