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埃塞俄比亚中南部治疗中心收治的新冠肺炎患者的康复时间及其相关因素。

Time to recovery from Covid-19 and its associated factors among patients hospitalized to the treatment center in South Central Ethiopia.

作者信息

Kaso Abdene Weya, Hareru Habtamu Endashaw, Kaso Taha, Agero Gebi

机构信息

School of Public Health, College of Medicine and Health Science, Dilla University, Ethiopia.

Departments of Surgery, College of Health Science, Arsi University, Ethiopia.

出版信息

Environ Chall (Amst). 2022 Jan;6:100428. doi: 10.1016/j.envc.2021.100428. Epub 2021 Dec 16.

Abstract

Coronavirus outbreak was a public health emergency. The surge of new confirmed cases and deaths was observed in developing countries due to the occurrence of new variants. However, factors associated with the duration of recovery among admitted patients remained uncertain. Therefore, we assessed factors associated with time to recovery from Covid-19 among hospitalized patients at the treatment center in South Central, Ethiopia. We employed a retrospective cross-sectional study among 422 patients hospitalized at Bokoji Hospital treatment center with Covid-19 from July 1, 2020, through October 30, 2021. Data were entered, coded, and analyzed using SPSS 26 version. We computed the survival probability using the Kaplan Meier method and determined factors associated with time to recovery using Cox regression analysis. Finally, the interpretation of adjusted hazard ratio (AHR) with 95% Confidence Interval (CI) and P-values less than 0.05 were declared as statistically significant. Our study found that the median time to recovery from Covid-19 infection of 13 days, with an IQR of 9-17 days. In multivariate Cox regression, ≥ 60 years old (AHR = 0.66; 95% CI: 0.49, 0.895), chronic pulmonary disease (AHR = 0.67; 95% CI: 0.455, 0.978), Male (AHR = 0.77; 95% CI: 0.611, 0.979), and being on Intranasal oxygen care (AHR = 0.56; 95% CI: 0.427-0.717) were significantly associated with time to recovery. Thus, health providers in treatment centers should give strict follow-up and priority for elders, patients with underlying diseases, and under supportive treatment during case management.

摘要

冠状病毒爆发是一场公共卫生突发事件。由于新变种的出现,发展中国家出现了新确诊病例和死亡人数的激增。然而,与入院患者康复时长相关的因素仍不明确。因此,我们评估了埃塞俄比亚中南部治疗中心住院的新冠肺炎患者康复时间的相关因素。我们对2020年7月1日至2021年10月30日在博科吉医院治疗中心因新冠肺炎住院的422名患者进行了一项回顾性横断面研究。使用SPSS 26版本录入、编码和分析数据。我们采用Kaplan Meier方法计算生存概率,并使用Cox回归分析确定与康复时间相关的因素。最后,将调整后危险比(AHR)及95%置信区间(CI)且P值小于0.05解释为具有统计学意义。我们的研究发现,新冠肺炎感染康复的中位时间为13天,四分位距为9至17天。在多变量Cox回归中,≥60岁(AHR = 0.66;95% CI:0.49,0.895)、慢性肺病(AHR = 0.67;95% CI:0.455,0.978)、男性(AHR = 0.77;95% CI:0.611,0.979)以及接受鼻内给氧护理(AHR = 0.56;95% CI:0.427 - 0.717)与康复时间显著相关。因此,治疗中心的医护人员在病例管理期间应给予老年人、患有基础疾病的患者以及接受支持性治疗的患者严格的随访和优先关注。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea8d/8673952/45a63cf2073f/gr1_lrg.jpg

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