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牙齿缺失是否与多种慢性病有关?

Is tooth loss associated with multiple chronic conditions?

机构信息

King's College London, London, UK.

出版信息

Acta Odontol Scand. 2023 Aug;81(6):443-448. doi: 10.1080/00016357.2023.2166986. Epub 2023 Jan 12.

DOI:10.1080/00016357.2023.2166986
PMID:36634031
Abstract

OBJECTIVES

To examine the relationship between tooth loss and co-occurrence of multiple chronic conditions (MCC) among American adults at working age.

MATERIALS AND METHODS

Data was from the Behavioural Risk Factor Surveillance System 2018, a cross-sectional telephone-based, nationally representative survey of American adults. We included participants aged 25-64 years. The survey included sociodemographic data, reported diagnosis of chronic conditions, the number of missing teeth and health behaviours. An aggregate variable of chronic conditions was created which included heart attack, angina, stroke, cancer, chronic pulmonary disease, diabetes, asthma, arthritis, depression, and kidney diseases. The association between the number of missing teeth and the aggregate of chronic conditions was assessed adjusting for confounders.

RESULTS

The analysis included 202,809 participants. The mean number of MCC was 0.86 (95% Confidence Interval 'CI':0.85,0.87). Tooth loss was significantly associated with MCC with rate ratio 1.18 (95% CI:1.15,1.21), 1.53 (95% CI:1.48,1.59) and 1.62 (95% CI:1.55,1.69) for those reporting losing 1-5 teeth, 6 or more but not all, and all teeth, respectively after adjusting for demographic, socioeconomic, and behavioural factors.

CONCLUSION

Tooth loss could be an early marker for the co-occurrence of multiple chronic conditions among adults of working age. The association could be attributed to common risk factors for oral and general health.

摘要

目的

研究美国成年工作人群中牙齿缺失与多种慢性疾病(MCC)共病的关系。

材料与方法

数据来自于 2018 年行为风险因素监测系统,这是一项针对美国成年人的基于电话的全国代表性横断面调查。我们纳入了 25-64 岁的参与者。该调查包括社会人口统计学数据、报告的慢性疾病诊断、缺失牙齿数量和健康行为。创建了一个慢性疾病综合变量,其中包括心脏病发作、心绞痛、中风、癌症、慢性肺部疾病、糖尿病、哮喘、关节炎、抑郁和肾脏疾病。在调整混杂因素后,评估了缺失牙齿数量与慢性疾病综合变量之间的关联。

结果

分析纳入了 202809 名参与者。平均 MCC 数量为 0.86(95%置信区间'CI':0.85,0.87)。牙齿缺失与 MCC 显著相关,比率比为 1.18(95% CI:1.15,1.21)、1.53(95% CI:1.48,1.59)和 1.62(95% CI:1.55,1.69),分别代表报告缺失 1-5 颗、6 颗或更多但并非全部、以及所有牙齿的人群。在调整人口统计学、社会经济和行为因素后。

结论

牙齿缺失可能是成年工作人群中多种慢性疾病共病的早期标志物。这种关联可能归因于口腔和全身健康的共同危险因素。

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