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妇产科中的增材制造和三维打印:全面综述。

Additive manufacturing and three-dimensional printing in obstetrics and gynecology: a comprehensive review.

机构信息

Koç University School of Medicine, Koç University, Sariyer, 34450, Istanbul, Turkey.

Department of Mechanical Engineering, Koç University, Sariyer, 34450, Istanbul, Turkey.

出版信息

Arch Gynecol Obstet. 2023 Dec;308(6):1679-1690. doi: 10.1007/s00404-023-06912-1. Epub 2023 Jan 13.

DOI:10.1007/s00404-023-06912-1
PMID:36635490
Abstract

Three-dimensional (3D) printing, also known as additive manufacturing, is a technology used to create complex 3D structures out of a digital model that can be almost any shape. Additive manufacturing allows the creation of customized, finely detailed constructs. Improvements in 3D printing, increased 3D printer availability, decreasing costs, development of biomaterials, and improved cell culture techniques have enabled complex, novel, and customized medical applications to develop. There have been rapid development and utilization of 3D printing technologies in orthopedics, dentistry, urology, reconstructive surgery, and other health care areas. Obstetrics and Gynecology (OBGYN) is an emerging application field for 3D printing. This technology can be utilized in OBGYN for preventive medicine, early diagnosis, and timely treatment of women-and-fetus-specific health issues. Moreover, 3D printed simulations of surgical procedures enable the training of physicians according to the needs of any given procedure. Herein, we summarize the technology and materials behind additive manufacturing and review the most recent advancements in the application of 3D printing in OBGYN studies, such as diagnosis, surgical planning, training, simulation, and customized prosthesis. Furthermore, we aim to give a future perspective on the integration of 3D printing and OBGYN applications and to provide insight into the potential applications.

摘要

三维(3D)打印,也称为增材制造,是一种使用数字模型创建复杂 3D 结构的技术,几乎可以是任何形状。增材制造允许创建定制的、精细的结构。3D 打印的改进、3D 打印机的可用性增加、成本降低、生物材料的发展以及细胞培养技术的改进,使得复杂、新颖和定制的医学应用得以发展。3D 打印技术在骨科、牙科、泌尿科、重建外科和其他医疗保健领域得到了快速发展和应用。妇产科(OBGYN)是 3D 打印的一个新兴应用领域。这项技术可以在妇产科中用于预防医学、早期诊断和及时治疗妇女和胎儿特有的健康问题。此外,手术过程的 3D 打印模拟可以根据特定手术的需要对医生进行培训。在此,我们总结了增材制造背后的技术和材料,并回顾了 3D 打印在妇产科研究中的最新应用进展,如诊断、手术规划、培训、模拟和定制假体。此外,我们旨在对 3D 打印与妇产科应用的整合进行未来展望,并深入探讨其潜在应用。

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ACS Omega. 2021 Sep 3;6(36):23067-23075. doi: 10.1021/acsomega.1c02117. eCollection 2021 Sep 14.
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3D Printing Techniques and Their Applications to Organ-on-a-Chip Platforms: A Systematic Review.
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Craniofacial phenotyping with fetal MRI: a feasibility study of 3D visualisation, segmentation, surface-rendered and physical models.胎儿 MRI 的颅面表型分析:3D 可视化、分割、表面渲染和物理模型的可行性研究。
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ACS Mater Au. 2023 Aug 28;3(6):620-635. doi: 10.1021/acsmaterialsau.3c00046. eCollection 2023 Nov 8.
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Bioengineering (Basel). 2023 Feb 27;10(3):299. doi: 10.3390/bioengineering10030299.
3D 打印技术及其在器官芯片平台中的应用:系统评价。
Sensors (Basel). 2021 May 10;21(9):3304. doi: 10.3390/s21093304.
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