Multi-scene visual hydrazine hydrate detection based on a dibenzothiazole derivative.

Hydrazine (NH) produced by industries is distributed into different environments, and seriously threatens ecology and human security. Hence, it is important to develop probes that detect NH in various environments. In this study, a novel NH fluorescent probe was prepared based on a dibenzothiazole derivative (DBTD). The obtained DBTD probe demonstrated a strong ratio of colorimetric detection of NH, a rapid response, and good selectivity and sensitivity (detection limit 0.438 μM). Based on its good performance, the DBTD probe was successfully applied for the determination of trace NH in water, cells, and zebrafish. In addition, the results of the fluorescence colocalization experiment demonstrated the lysosomal-targetable ability of DBTD.