Jason Leonard A, Dorri Joseph A
Center for Community Research, DePaul University, Chicago, IL 60614, USA.
Neurol Int. 2022 Dec 20;15(1):1-11. doi: 10.3390/neurolint15010001.
This study sought to ascertain the prevalence of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) among a sample of 465 patients with Long COVID. The participants completed three questionnaires: (1) a new questionnaire measuring both the frequency and severity of 38 common symptoms of COVID and Long COVID, (2) a validated short form questionnaire assessing ME/CFS, and (3) a validated questionnaire measuring post-exertional malaise. The population was predominantly white, female, and living in North America. The mean duration since the onset of COVID-19 symptoms was 70.5 weeks. Among the 465 participants, 58% met a ME/CFS case definition. Of respondents who reported that they had ME/CFS only 71% met criteria for ME/CFS and of those who did not report they had ME/CFS, 40% nevertheless did meet criteria for the disease: both over-diagnosis and under-diagnosis were evident on self-report. This study supports prior findings that ME/CFS occurs with high prevalence among those who have persistent COVID-19 symptoms.
本研究旨在确定465名新冠后综合征患者样本中肌痛性脑脊髓炎/慢性疲劳综合征（ME/CFS）的患病率。参与者完成了三份问卷：（1）一份新问卷，用于测量新冠和新冠后38种常见症状的频率和严重程度；（2）一份经过验证的简短问卷，用于评估ME/CFS；（3）一份经过验证的问卷，用于测量运动后不适。研究人群主要为白人、女性，居住在北美。自新冠症状出现以来的平均持续时间为70.5周。在465名参与者中，58%符合ME/CFS病例定义。在报告患有ME/CFS的受访者中，只有71%符合ME/CFS标准，而在未报告患有ME/CFS的受访者中，40%确实符合该疾病标准：自我报告中过度诊断和诊断不足均很明显。本研究支持先前的研究结果，即ME/CFS在持续出现新冠症状的人群中患病率很高。
