Peralta-Pedrero María L, Guerrero-Oliva Germán, Morales-Sánchez Martha A, Chirino-Castillo Georgina Q, Marín-Rivera Daniela, Núñez-Benítez Miguel A, Santa-Cruz Fermín J
Centro Dermatológico "Dr Ladislao de la Pascua", Research Unit.
Family Medicine Unit 31, Instituto Mexicano del Seguro Social. Mexico City, Mexico.
Gac Med Mex. 2022;158(6):393-400. doi: 10.24875/GMM.M22000718.
Vitiligo is an incurable, slowly progressive skin condition, the prevalence of which ranges from 0.4 to 2.0%. Health-related quality of life (HRQoL) refers to self-perceived well-being associated with the presence of a disease and its treatment.
Cross-sectional study at a dermatological center. Adults with non-segmental vitiligo (NSV) were included, while patients with other pigmentary disorders and other types of vitiligo were excluded. The VitiQoL questionnaire (0 = no skin involvement, 90 = maximum skin involvement), the Vitiligo Extent Score (VES) and the Vitiligo Area Scoring Index (VASI) were applied.
492 patients did participate; 63% were women. An average score of 32.6 was obtained on VitiQoL (95% CI = 30.6-34.5). Self-perception of severity and HRQoL were correlated (r = 0.568, p < 0.001). Age, the female gender, lower education and higher self-perceived severity were associated with poorer HRQoL. The proportion of subjects who reported an addiction was similar in the worst and best HRQoL groups (28% vs. 32%, p = 0.23).
Poorer HRQoL is explained by severity self-perception, concern about disease progression, appearance of the skin and necessary actions to avoid sun exposure during recreation.
白癜风是一种无法治愈、进展缓慢的皮肤疾病，其患病率在0.4%至2.0%之间。健康相关生活质量（HRQoL）指的是与疾病及其治疗相关的自我感知幸福感。
在一家皮肤科中心进行横断面研究。纳入非节段性白癜风（NSV）成人患者，排除患有其他色素沉着紊乱及其他类型白癜风的患者。应用VitiQoL问卷（0=无皮肤受累，90=最大程度皮肤受累）、白癜风面积评分（VES）和白癜风面积评分指数（VASI）。
492名患者参与研究；63%为女性。VitiQoL问卷平均得分为32.6（95%置信区间=30.6-34.5）。严重程度的自我认知与健康相关生活质量相关（r=0.568，p<0.001）。年龄、女性、低学历以及较高的自我感知严重程度与较差的健康相关生活质量相关。在健康相关生活质量最差和最佳的组中，报告有上瘾情况的受试者比例相似（28%对32%，p=0.23）。
较差的健康相关生活质量可由严重程度的自我认知、对疾病进展的担忧、皮肤外观以及在娱乐期间避免阳光照射的必要措施来解释。
