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内在能力与恢复力:将衰弱研究提升到新高度。

Intrinsic capacity and resilience: Taking frailty to the next level.

作者信息

Hamaker Marije, Gijzel Sanne, Rostoft Siri, van den Bos Frederiek

机构信息

Department of Geriatric Medicine, Diakonessenhuis Utrecht, the Netherlands.

Vivum Naaderheem Geriatric Rehabilitation Center, Naarden, the Netherlands.

出版信息

J Geriatr Oncol. 2023 Mar;14(2):101421. doi: 10.1016/j.jgo.2022.101421. Epub 2023 Jan 17.

DOI:10.1016/j.jgo.2022.101421
PMID:36657249
Abstract

In addition to frailty, two novel concepts have been introduced in the field of geriatrics to capture the heterogeneous ageing process: the first is intrinsic capacity, which uses a community-based, holistic approach and is propagated by the World Health Organization (WHO); and the second is resilience, which provides a more dynamic perspective on the individual's reserves, injury and recovery. While both concepts are linked to frailty, with all three focusing on reserves in relation to ageing, each approaches this issue from a different point of view. In this paper, we will compare and contrast these three concepts - frailty, intrinsic capacity and resilience - and assess their relevance to future geriatric oncology research as well as daily clinical practice.

摘要

除了衰弱之外,老年医学领域还引入了两个新概念来描述异质性衰老过程:第一个是内在能力,它采用基于社区的整体方法,由世界卫生组织(WHO)推广;第二个是恢复力,它为个体的储备、损伤和恢复提供了更动态的视角。虽然这两个概念都与衰弱相关,且三者都关注与衰老相关的储备,但它们从不同的角度来探讨这个问题。在本文中,我们将比较和对比衰弱、内在能力和恢复力这三个概念,并评估它们与未来老年肿瘤学研究以及日常临床实践的相关性。

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Front Aging. 2025 Jul 1;6:1520842. doi: 10.3389/fragi.2025.1520842. eCollection 2025.
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Impact of impaired intrinsic capacity on postoperative frailty in elderly patients undergoing colorectal surgery: study protocol for a single-center, prospective, cohort study.内在能力受损对老年结直肠癌手术患者术后虚弱的影响:一项单中心、前瞻性队列研究的研究方案
Front Aging Neurosci. 2025 May 12;17:1523642. doi: 10.3389/fnagi.2025.1523642. eCollection 2025.
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Sarcopenia and frailty in critical illness.
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Curr Opin Clin Nutr Metab Care. 2025 May 1;28(3):192-199. doi: 10.1097/MCO.0000000000001123. Epub 2025 Mar 12.
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Multidimensional frailty as a predictor of mortality among older adults: a systematic review and meta-analysis.多维脆弱性作为老年人死亡率的预测指标:系统评价和荟萃分析。
BMC Geriatr. 2024 Sep 28;24(1):793. doi: 10.1186/s12877-024-05377-4.