He Xin-Qi, Qiu Hui-Qing, Wang Meng, Mao Ya-Fei, Li Xin-Yuan, Wang Xian-Yun, Geng Yu-Lan, Wang Le
Department of Vascular Surgery, The First Hospital of Hebei Medical University, Shijiazhuang, People's Republic of China.
Department of Neurology, The First Hospital of Hebei Medical University, Shijiazhuang, People's Republic of China.
Infect Drug Resist. 2023 Jan 12;16:243-248. doi: 10.2147/IDR.S396269. eCollection 2023.
A thoracic aortic aneurysm (TAA) is a known condition seen in cardiovascular practice. A TAA rupture and postoperative infection may result in death. Preoperative infections leading to death are extremely rare.
A 62-year-old Chinese female was admitted to The First Hospital of Hebei Medical University with a two-day history of abdominal pain. She was diagnosed with a TAA rupture and underwent immediate surgery. The preoperative urine analysis indicated that the positive bacteria and white blood cell count suggested a urinary tract bacterial infection. The patient was administered the empiric antibiotics, cefazolin; however, her blood pressure continued to drop during the perioperative period and she died of uncorrectable acidosis 8 h after the operation. On the second day after death, both the blood and urine cultures were positive for .
Given that this patient with a TAA rupture died of uncorrected acidosis caused by preoperative infection, it is important to evoke the diagnosis in the context of TAA. Routine laboratory indicators are valuable factors for surgeons and physicians in assessing a patient's condition and improving their prognosis.
胸主动脉瘤（TAA）是心血管临床中常见的病症。TAA破裂及术后感染可能导致死亡。术前感染导致死亡极为罕见。
一名62岁中国女性因腹痛两天入住河北医科大学第一医院。她被诊断为TAA破裂并立即接受手术。术前尿液分析显示，阳性菌及白细胞计数提示存在泌尿系统细菌感染。给予患者经验性抗生素头孢唑林治疗；然而，围手术期她的血压持续下降，术后8小时死于无法纠正的酸中毒。死亡后第二天，血培养和尿培养均为……阳性。
鉴于该TAA破裂患者死于术前感染引起的未纠正酸中毒，在TAA背景下进行诊断很重要。常规实验室指标对于外科医生和内科医生评估患者病情及改善其预后是有价值的因素。
