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马来西亚半岛物种研究综述

A Review of Studies on Species in Peninsular Malaysia.

作者信息

Farooq Humaira, Monowar Tahmina, Latt Swe Swe, Chinni Suresh V, Zainol Noor Hasliza, Sabesan Gokul Shankar

机构信息

Faculty of Medicine, AIMST University, Malaysia.

Faculty of Medicine, RCSI and UCD Malaysia Campus, Penang, Malaysia.

出版信息

Adv Biomed Res. 2022 Nov 28;11:98. doi: 10.4103/abr.abr_3_22. eCollection 2022.

Abstract

Data on the epidemiology and the antifungal susceptibility of species infections in Malaysia is still limited. The study aimed to review and compare studies reporting the prevalence of species and antifungal susceptibility of infections in Peninsular Malaysia. Data from 22 studies published between 2009 and 2018. Data was collected using National Center for Biotechnology Information and Google Scholar using the keywords " and Malaysia." Around 19 species were identified in a total of 35,608 isolates analyzed in these studies. In most studies examined, (66.3%) was the predominant species, followed by (11.7%), (10.7%), (9.5%), and (1.19%). Vaginal swabs yielded the most isolates, followed by the respiratory system, urine, blood, oral, pus, and other locations. The demographic, racial, and gender data were recorded only in two studies. Totally, eight studies examined 396 isolates for antifungal susceptibility to common antifungal medications. The average antifungal susceptibility of isolates and efficacy of drugs in these studies ranged between 45 and 99% for most common antifungal drugs. Caspofungin had the highest susceptibility at 99%, whereas itraconazole had the lowest at only 45%. Overall, this review provided a comprehensive summary of all the current research on predominant species in Peninsular Malaysia.

摘要

马来西亚有关物种感染的流行病学和抗真菌药敏性的数据仍然有限。该研究旨在回顾和比较报告马来西亚半岛物种流行率和感染抗真菌药敏性的研究。数据来自2009年至2018年间发表的22项研究。使用美国国立生物技术信息中心和谷歌学术搜索引擎,通过关键词“和马来西亚”收集数据。在这些研究分析的总共35,608个分离株中鉴定出约19种物种。在大多数所检查的研究中,(66.3%)是主要物种,其次是(11.7%)、(10.7%)、(9.5%)和(1.19%)。阴道拭子产生的分离株最多,其次是呼吸系统、尿液、血液、口腔、脓液和其他部位。仅在两项研究中记录了人口统计学、种族和性别数据。总共八项研究检查了396个分离株对常见抗真菌药物的药敏性。在这些研究中,分离株的平均抗真菌药敏性和药物疗效对于大多数常见抗真菌药物而言在45%至99%之间。卡泊芬净的药敏性最高,为99%,而伊曲康唑最低,仅为45%。总体而言,本综述全面总结了目前关于马来西亚半岛主要物种的所有研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8409/9843594/77a7ac3d9fdf/ABR-11-98-g001.jpg

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