Morton K, Robertson A J, Hadden W
Department of Pathology, Perth Royal Infirmary, Scotland, UK.
Histopathology. 1987 Sep;11(9):963-9. doi: 10.1111/j.1365-2559.1987.tb01902.x.
A case of angiolymphoid hyperplasia with eosinophilia arising from the radial artery is presented. Histologically, there was proliferation of atypical endothelial cells forming vascular spaces and solid cords, with a background infiltrate of inflammatory cells and prominent tissue eosinophilia. Immunohistochemical studies demonstrated vimentin and factor VIII related antigen in the endothelial cells. The lymphoid infiltrate was polyclonal. These lesions, which typically occur in the dermis and subcutaneous tissue of the head and neck, are known by a variety of different names reflecting disagreement regarding their pathogenesis. The probable nature of the process is discussed.
本文报告1例起源于桡动脉的伴有嗜酸性粒细胞增多的血管淋巴样增生病例。组织学上，可见非典型内皮细胞增生，形成血管腔隙和实性条索，伴有炎性细胞浸润背景及显著的组织嗜酸性粒细胞增多。免疫组织化学研究显示内皮细胞中波形蛋白和第Ⅷ因子相关抗原阳性。淋巴样浸润为多克隆性。这些病变通常发生于头颈部真皮和皮下组织，因对其发病机制存在分歧而有多种不同的命名。文中讨论了该病变可能的性质。
