Division of Food Additives, National Institute of Health Sciences, Tokyo, Japan.
Sapporo City Institute of Public Health, Sapporo, Japan.
Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2023 Mar;40(3):328-345. doi: 10.1080/19440049.2023.2167002. Epub 2023 Jan 20.
To estimate the daily intake of food additives by young children aged 1-6 years in Japan, an intake survey was conducted in 2018 using the market basket method for food additives, including twelve types of colourants, three kinds of preservatives, three kinds of sweeteners and two kinds of food manufacturing agents. A list of the daily consumption of processed foods was prepared based on a special survey (MHLW 2011) and used for the estimation. The results of the survey showed that the food additives with the highest daily intake were phosphorus compounds (phosphoric acid and its salts; 11.2 mg/kg bw/day, expressed as phosphorus), followed by propylene glycol (0.80 mg/kg bw/day). The daily intake of other food additives ranged from 0 to 0.20 mg/kg bw/day. The estimated daily intake of each food additives by young children was compared with the acceptable daily intake (ADI) or maximum tolerable daily intake (MTDI). The highest ratio of the estimated daily intake to ADI was 3.2% for propylene glycol, whereas the ratios of the estimated daily intake to ADI for colourants, preservatives and sweeteners ranged from 0 to 1.1% (benzoic acid). The ratio of the estimated daily intake to MTDI for phosphorus compounds was 16%.
为了估算日本 1-6 岁幼儿每日摄入的食品添加剂,我们于 2018 年采用食品添加剂的购物篮法进行了一项摄入量调查,其中包括 12 种着色剂、3 种防腐剂、3 种甜味剂和 2 种食品加工助剂。我们根据一项专项调查(MHLW 2011)编制了一份加工食品日消耗量清单,用于估算摄入量。调查结果显示,摄入量最高的食品添加剂是磷化合物(磷酸及其盐;以磷计,11.2mg/kg bw/day),其次是丙二醇(0.80mg/kg bw/day)。其他食品添加剂的日摄入量在 0 至 0.20mg/kg bw/day 之间。我们将幼儿的每种食品添加剂估计摄入量与每日允许摄入量(ADI)或最大耐受日摄入量(MTDI)进行了比较。丙二醇的估计日摄入量与 ADI 的比值最高,为 3.2%,而着色剂、防腐剂和甜味剂的估计日摄入量与 ADI 的比值在 0 至 1.1%(苯甲酸)之间。磷化合物的估计日摄入量与 MTDI 的比值为 16%。