Child J A, Cooper E H, Illingworth S, Worthy T S
Recent Results Cancer Res. 1978;64:180-9. doi: 10.1007/978-3-642-81246-0_20.
Vertical studies indicate that, in general, acute phase reactant proteins (APRP) reflect disease activity in both Hodgkin's disease and non-Hodgkin's lymphoma. Longitudinal studies of the selected APRP profile demonstrate the following: 1. The stable profile is characteristic of remission. 2. Considerable elevation of APRPs coincides with relapsed disease. 3. An unstable profile is a feature of relapsing disease and may give early warning of relapse. 4. Patients responding inadequately to treatment frequently have unstable APRP profiles.
纵向研究表明，一般来说，急性期反应蛋白（APRP）可反映霍奇金病和非霍奇金淋巴瘤的疾病活动情况。对选定的APRP谱进行的纵向研究显示如下：1. 稳定的谱是缓解期的特征。2. APRP显著升高与疾病复发相符。3. 不稳定的谱是复发性疾病的一个特征，可能会给出复发的早期预警。4. 对治疗反应不佳的患者APRP谱通常不稳定。
