来自印度全国性痴呆研究的深度表型和基因组数据。
Deep phenotyping and genomic data from a nationally representative study on dementia in India.
机构信息
Center for Economic and Social Research, University of Southern California, Los Angeles, CA, USA.
Department of Geriatric Medicine, All India Institute of Medical Sciences, New Delhi, India.
出版信息
Sci Data. 2023 Jan 20;10(1):45. doi: 10.1038/s41597-023-01941-6.
The Harmonized Diagnostic Assessment of Dementia for the Longitudinal Aging Study in India (LASI-DAD) is a nationally representative in-depth study of cognitive aging and dementia. We present a publicly available dataset of harmonized cognitive measures of 4,096 adults 60 years of age and older in India, collected across 18 states and union territories. Blood samples were obtained to carry out whole blood and serum-based assays. Results are included in a venous blood specimen datafile that can be linked to the Harmonized LASI-DAD dataset. A global screening array of 960 LASI-DAD respondents is also publicly available for download, in addition to neuroimaging data on 137 LASI-DAD participants. Altogether, these datasets provide comprehensive information on older adults in India that allow researchers to further understand risk factors associated with cognitive impairment and dementia.
《印度纵向老龄化研究中的痴呆症综合诊断评估》（LASI-DAD）是一项针对认知老化和痴呆的全国代表性深入研究。我们提供了一个公开的数据集，其中包含 4096 名 60 岁及以上印度成年人的协调认知测量结果，这些数据来自印度 18 个邦和联邦属地。采集了血液样本以进行全血和血清检测。结果包含在静脉血标本数据文件中，可以与协调的 LASI-DAD 数据集关联。此外，还可以下载 LASI-DAD 960 名受访者的全球筛选阵列，以及 137 名 LASI-DAD 参与者的神经影像学数据。这些数据集总共为印度的老年人提供了全面的信息，使研究人员能够进一步了解与认知障碍和痴呆症相关的风险因素。
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