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胶质瘤的发病机制研究:从胶质瘤干细胞、基因组标签到啮齿动物模型

Pathogenesis Study of Glioma: From Glioma Stem Cells, Genomic Tags, to Rodent Models.

作者信息

Tang Hailiang, Li Xi, Xie Rong

机构信息

Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, No. 12 Wulumuqi Middle Road, Shanghai 200040, China.

National Center for Neurological Disorders, Shanghai 200040, China.

出版信息

Brain Sci. 2022 Dec 23;13(1):30. doi: 10.3390/brainsci13010030.

DOI:10.3390/brainsci13010030
PMID:36672013
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9856728/
Abstract

Glioma remains the toughest brain tumor among all primary central nervous system (CNS) tumors [...].

摘要

在所有原发性中枢神经系统(CNS)肿瘤中,胶质瘤仍然是最难治疗的脑部肿瘤[...]。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5bb9/9856728/f27a49eb10b1/brainsci-13-00030-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5bb9/9856728/f27a49eb10b1/brainsci-13-00030-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5bb9/9856728/f27a49eb10b1/brainsci-13-00030-g001.jpg

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本文引用的文献

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Glioma: molecular signature and crossroads with tumor microenvironment.神经胶质瘤:分子特征与肿瘤微环境的交汇点。
Cancer Metastasis Rev. 2022 Mar;41(1):53-75. doi: 10.1007/s10555-021-09997-9. Epub 2021 Oct 23.
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Editorial: Neural Stem Cells of the Subventricular Zone: From Neurogenesis to Glioblastoma Origin.社论:脑室下区神经干细胞:从神经发生到胶质母细胞瘤起源
Front Oncol. 2021 Sep 17;11:750116. doi: 10.3389/fonc.2021.750116. eCollection 2021.
3
Rodent Models to Analyze the Glioma Microenvironment.用于分析胶质瘤微环境的啮齿动物模型
ASN Neuro. 2021 Jan-Dec;13:17590914211005074. doi: 10.1177/17590914211005074.
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Contemporary Mouse Models in Glioma Research.当代神经胶质瘤研究中的小鼠模型
Cells. 2021 Mar 23;10(3):712. doi: 10.3390/cells10030712.
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Targeting Glioma Stem Cells.靶向神经胶质瘤干细胞。
Neurosurg Clin N Am. 2021 Apr;32(2):283-289. doi: 10.1016/j.nec.2021.01.002. Epub 2021 Feb 18.
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Glioma Stem Cells as Immunotherapeutic Targets: Advancements and Challenges.作为免疫治疗靶点的胶质瘤干细胞:进展与挑战
Front Oncol. 2021 Feb 24;11:615704. doi: 10.3389/fonc.2021.615704. eCollection 2021.
7
Observations on the anti-glioma potential of electrical fields: is there a role for surgical neuromodulation?电场抗神经胶质瘤作用的观察:神经外科调控是否有作用?
Br J Neurosurg. 2022 Oct;36(5):564-568. doi: 10.1080/02688697.2021.1886242. Epub 2021 Feb 13.
8
The Subventricular Zone, a Hideout for Adult and Pediatric High-Grade Glioma Stem Cells.室管膜下区,成人和儿童高级别胶质瘤干细胞的藏身之处。
Front Oncol. 2021 Jan 26;10:614930. doi: 10.3389/fonc.2020.614930. eCollection 2020.
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The Glioma Stem Cell Model in the Era of Single-Cell Genomics.单细胞基因组学时代的神经胶质瘤干细胞模型。
Cancer Cell. 2020 May 11;37(5):630-636. doi: 10.1016/j.ccell.2020.04.001.
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Patient-Derived Glioma Models: From Patients to Dish to Animals.患者来源的脑胶质瘤模型:从患者到培养皿再到动物。
Cells. 2019 Sep 30;8(10):1177. doi: 10.3390/cells8101177.