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子痫前期与肥胖——运动的预防作用。

Preeclampsia and Obesity-The Preventive Role of Exercise.

机构信息

Chair and Department of Obstetrics and Perinatology, Medical University of Lublin, 20-954 Lublin, Poland.

出版信息

Int J Environ Res Public Health. 2023 Jan 10;20(2):1267. doi: 10.3390/ijerph20021267.

Abstract

Obesity is now recognized as a worldwide epidemic. An inadequate diet and reduced physical activity are acknowledged as the leading causes of excess body weight. Despite growing evidence that obesity is a risk factor for unsuccessful pregnancies, almost half of all women who become pregnant today are overweight or obese. Common complications of pregnancy in this group of women are preeclampsia and gestational hypertension. These conditions are also observed more frequently in women with excessive weight gain during pregnancy. Preeclampsia is one of the most serious pregnancy complications with an unpredictable course, which in its most severe forms, threatens the life and health of the mother and her baby. The early identification of the risk factors for preeclampsia development, including obesity, allows for the implementation of prophylaxis and a reduction in maternal and fetal complications risk. Additionally, preeclampsia and obesity are the recognized risk factors for developing cardiovascular disease in later life, so prophylaxis and treating obesity are paramount for their prevention. Thus, a proper diet and physical activity might play an essential role in the prophylaxis of preeclampsia in this group of women. Limiting weight gain during pregnancy and modifying the metabolic risk factors with regular physical exercise creates favorable metabolic conditions for pregnancy development and benefits the elements of the pathogenetic sequence for preeclampsia development. In addition, it is inexpensive, readily available and, in the absence of contraindications to its performance, safe for the mother and fetus. However, for this form of prevention to be effective, it should be applied early in pregnancy and, for overweight and obese women, proposed as an essential part of planning pregnancy. This paper aims to present the mechanisms of the development of hypertension in pregnancy in obese women and the importance of exercise in its prevention.

摘要

肥胖现在被认为是一种全球性的流行病。饮食不足和体力活动减少被认为是导致体重过重的主要原因。尽管越来越多的证据表明肥胖是妊娠不成功的危险因素,但今天几乎一半的孕妇超重或肥胖。在这群女性中,妊娠的常见并发症是子痫前期和妊娠高血压。在怀孕期间体重过度增加的女性中,也更频繁地观察到这些情况。子痫前期是最严重的妊娠并发症之一,具有不可预测的病程,在最严重的情况下,会威胁到母亲和她的婴儿的生命和健康。早期识别子痫前期发展的危险因素,包括肥胖,可以进行预防,并降低母婴并发症的风险。此外,子痫前期和肥胖是日后发生心血管疾病的公认危险因素,因此预防和治疗肥胖对于预防这些疾病至关重要。因此,适当的饮食和体育锻炼可能在预防这群女性的子痫前期中发挥重要作用。限制怀孕期间的体重增加,并通过定期体育锻炼改变代谢危险因素,为妊娠的发展创造有利的代谢条件,并有利于子痫前期发展的发病机制的各个环节。此外,它价格低廉、易于获得,在没有禁忌症的情况下,对母亲和胎儿都是安全的。然而,为了使这种预防措施有效,它应该在怀孕早期应用,对于超重和肥胖的女性,应该将其作为妊娠计划的重要组成部分来提出。本文旨在介绍肥胖孕妇妊娠高血压的发病机制以及运动在其预防中的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c284/9859423/dd1c354beb66/ijerph-20-01267-g001.jpg

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