Li Dandan, Wen Qilin, Zhou Yanyu, Li Dan, Xi Huai, Huang Guidan, Liang Jinhua, Xiao Xiaofen, Zhu Wenyuan
College of Chemistry and Bioengineering, Guilin University of Technology, Guangxi, 541004, China.
Key Laboratory of Carbon Materials of Zhejiang Province, College of Chemistry and Materials Engineering, Wenzhou University, Wenzhou, 325035, Zhejiang, China.
Anal Sci. 2023 Apr;39(4):565-571. doi: 10.1007/s44211-023-00273-0. Epub 2023 Jan 21.
Mercury ion (Hg) is the most widespread and highly toxic environmental pollutant, which exerts numerous adverse effects on environmental and human health. There is an urgent need to develop a convenient method for detecting Hg. Herein, a novel dual-mode sensor based on colorimetric and Tyndall effect of gold nanoparticles was developed for ultra-sensitive determination of Hg. In this strategy, a polyA-modified Au probe with high uniformity was assembled successfully. Both modes were based on Hg-induced aggregation of the probes. Hg was reflected according to the color variations of solution and the Tyndall effect of Au reporter. With the aid of a laser pointer, the Tyndall mode demonstrated about 615-fold improvement on sensitivity compared with the colorimetry way. Taking advantages of low cost and convenient assembly of polyA-based Au probe and the combination of colorimetry and Tyndall effect, our strategy determined the Hg with high sensitivity and wide range. By changing probes or nanoparticles, the proposed strategy is expected to be a universal platform for detecting other analytes in environmental and even biological samples. A novel dual-mode sensor based on colorimetric and tyndall effect of gold nanoparticles for ultra-sensitive determination of Hg2+ was exploited.
汞离子（Hg）是分布最广且毒性极强的环境污染物，对环境和人类健康产生诸多不利影响。迫切需要开发一种便捷的汞检测方法。在此，基于金纳米颗粒的比色和廷德尔效应开发了一种新型双模式传感器，用于超灵敏测定汞。在该策略中，成功组装了具有高均匀性的聚腺苷酸修饰金探针。两种模式均基于汞诱导的探针聚集。通过溶液颜色变化和金报告分子的廷德尔效应来反映汞的含量。借助激光笔，廷德尔模式的灵敏度比比色法提高了约615倍。利用基于聚腺苷酸的金探针成本低且组装方便以及比色法和廷德尔效应相结合的优势，我们的策略能够高灵敏度、宽范围地测定汞。通过改变探针或纳米颗粒，所提出的策略有望成为检测环境甚至生物样品中其他分析物的通用平台。开发了一种基于金纳米颗粒的比色和廷德尔效应的新型双模式传感器，用于超灵敏测定Hg2+。
