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疼痛对子宫恶性肿瘤患者术后康复影响的研究

Study of the effect of pain on postoperative rehabilitation of patients with uterine malignant tumor.

作者信息

Lv Xiaohong, Li Chunlai, Tang Min, Yuan Dan, Zhong Yu, Xie Yubo

机构信息

Department of Anesthesiology, The First Affiliated Hospital of Guangxi Medical University, Guangxi, China.

Guangxi key Laboratory of Enhanced Recovery after Surgery for Gastrointestinal Cancer, The First Affiliated Hospital of Guangxi Medical University, Guangxi, China.

出版信息

Front Surg. 2023 Jan 4;9:1052800. doi: 10.3389/fsurg.2022.1052800. eCollection 2022.

Abstract

OBJECTIVE

The relationship between acute postoperative pain (APSP) and health-related quality of life (HRQoL) in patients with uterine malignant tumor after operation was evaluated with self-rating scales, and the influencing factors of postoperative rehabilitation were screened.

METHODS

A total of 102 patients undergoing elective surgery for Gynecology in the First Affiliated Hospital of Guangxi Medical University were included in this study. PCS, SAS, NRS and EQ-5D scales were evaluated 1 day before surgery, and NRS and EQ-5D scales were evaluated 1,3,7,14, and 30 days after surgery. In addition, the general and perioperative information of patients was collected from the medical record system of the hospital.

RESULTS

From the 1st to the 30th day after operation, the NRS and EQ-5D-5L scores of patients decreased gradually, and EQ-VAS scores increased gradually. NRS score was correlated with EQ-5D score ( < 0.01). Postoperative hospital stay, Education level, PCS score and NRS score (Overall state and Active state) were the principal influencing factors of EQ-5D score ( < 0.05). Patients in the pain group had a later time to get out of bed and eat, a higher incidence of postoperative complications, and a longer postoperative hospital stay ( < 0.05). Endoscopic surgery can reduce postoperative pain and promote postoperative rehabilitation ( = 37.631,  < 0.001).

CONCLUSIONS

The postoperative rehabilitation of patients in the pain group was poor. Minimally invasive surgery can reduce postoperative pain and promote postoperative rehabilitation. EQ-5D score can be used as a subjective index to evaluate postoperative rehabilitation.

TRIAL REGISTRATION

Chinese Clinical Trial Registry (identifier: ChiCTR2000032759).

摘要

目的

采用自评量表评估子宫恶性肿瘤患者术后急性疼痛(APSP)与健康相关生活质量(HRQoL)的关系,并筛选术后康复的影响因素。

方法

本研究纳入广西医科大学第一附属医院102例行择期妇科手术的患者。术前1天评估PCS、SAS、NRS和EQ-5D量表,术后1、3、7、14和30天评估NRS和EQ-5D量表。此外,从医院病历系统收集患者的一般及围手术期信息。

结果

术后第1天至第30天,患者的NRS和EQ-5D-5L评分逐渐降低,EQ-VAS评分逐渐升高。NRS评分与EQ-5D评分相关(<0.01)。术后住院时间、教育程度、PCS评分和NRS评分(总体状态和活动状态)是EQ-5D评分的主要影响因素(<0.05)。疼痛组患者下床和进食时间较晚,术后并发症发生率较高,术后住院时间较长(<0.05)。内镜手术可减轻术后疼痛,促进术后康复(=37.631,<0.001)。

结论

疼痛组患者术后康复较差。微创手术可减轻术后疼痛,促进术后康复。EQ-5D评分可作为评估术后康复的主观指标。

试验注册

中国临床试验注册中心(标识符:ChiCTR2000032759)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78c2/9847568/592387dcd5f7/fsurg-09-1052800-g001.jpg

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