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腹腔镜辅助经裂孔食管切除术:一家三级医疗中心10年的经验。

Laparoscopic-assisted transhiatal oesophagectomy: An experience from a tertiary care centre over 10 years.

作者信息

Kanchodu Sudheer, Nag Hirdaya Hulas

机构信息

Department of GI Surgery, GB Pant Institute of Post Graduate Medical Education and Research, New Delhi, India.

出版信息

J Minim Access Surg. 2023 Jul-Sep;19(3):378-383. doi: 10.4103/jmas.jmas_169_22.

Abstract

BACKGROUND

Minimally invasive surgeries have become the standard of care in oesophageal surgeries, but the transhiatal approach is still not widely in practice. As in the open surgical approach, laparoscopic transhiatal oesophagectomy has been accepted by many centres worldwide. The laparoscopic-assisted transhiatal oesophagectomy (LATE) has become a time-tested surgery. Many centres across the world have shown its feasibility and superiority regarding the lymph node yield with less morbidity with the added advantage of laparoscopy. We are pleased to share our 10-year experience with LATE and the long-term follow-up.

MATERIALS AND METHODS

Retrospective analysis of prospectively maintained data from our tertiary care centre from January 2010 to January 2021. Forty-six out of 74 patients with carcinoma of the lower end of the oesophagus who underwent LATE were analysed retrospectively.

RESULTS

Our study group included 46 patients. Six patients who required conversion to open surgery and those who underwent different procedures were excluded. The mean operative time was 220 (140-360) min. The mean blood loss was 230 (100-500) ml. Four (8.69%) patients had neck leaks. Twelve (26.08%) patients had minor pulmonary complications and one (2.17%) patient had a major pulmonary complication in the form of acute respiratory distress syndrome. The median hospital stay was 10.5 (8-28) days and 90-day mortality was 2.17%. 45 (97.82%) patients had an R0 resection rate with a median lymph node yield of 21 (16-28). The median overall survival was 44 months, with a 3 years disease-free survival rate of 63.04% and a 5-year overall survival rate of 36.50%.

CONCLUSION

LATE is feasible and safe for adenocarcinoma of lower third esophagus and GEJ (gastroesophageal junction). The laparoscopic magnified view of lower mediastinum provides a better vision for lymphadenectomy especially in the neoadjuvant group. It has all the added benefits of minimal invasive surgery with acceptable short and long term oncological results.

摘要

背景

微创手术已成为食管手术的标准治疗方式,但经裂孔手术仍未广泛应用。与开放手术方式一样,腹腔镜经裂孔食管切除术已被全球许多中心所接受。腹腔镜辅助经裂孔食管切除术(LATE)已成为一种经过时间考验的手术。世界各地的许多中心都展示了其在淋巴结清扫方面的可行性和优越性,发病率较低,且具有腹腔镜手术的额外优势。我们很高兴分享我们在LATE方面的10年经验及长期随访结果。

材料与方法

对我们三级医疗中心2010年1月至2021年1月前瞻性收集的数据进行回顾性分析。对74例行LATE的食管下端癌患者中的46例进行回顾性分析。

结果

我们的研究组包括46例患者。排除6例需要转为开放手术的患者以及接受不同手术的患者。平均手术时间为220(140 - 360)分钟。平均失血量为230(100 - 500)毫升。4例(8.69%)患者出现颈部漏。12例(26.08%)患者出现轻微肺部并发症,1例(2.17%)患者出现以急性呼吸窘迫综合征形式的严重肺部并发症。中位住院时间为10.5(8 - 28)天,90天死亡率为2.17%。45例(97.82%)患者R0切除率,中位淋巴结清扫数为21(16 - 28)。中位总生存期为44个月,3年无病生存率为63.04%,5年总生存率为36.50%。

结论

LATE对于食管下三分之一腺癌和胃食管交界部癌是可行且安全的。腹腔镜对下纵隔的放大视野为淋巴结清扫提供了更好的视野,尤其是在新辅助治疗组。它具有微创手术的所有额外益处,短期和长期肿瘤学结果均可接受。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eba5/10449055/b4dd1130f3bb/JMAS-19-378-g001.jpg

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