Deng Yujiao, Wang Ya, Zhang Yan, Yang Na, Ji Xingli, Wu Bing
Department of Radiology, West China Hospital, Sichuan University, Chengdu, China.
Department of Radiology, Chengdu Fifth People's Hospital, Chengdu, China.
Front Oncol. 2023 Jan 9;12:1018617. doi: 10.3389/fonc.2022.1018617. eCollection 2022.
Osteoclast-like giant cell tumor (OGCT) is a common bone tumor, occasionally observed in some extraosseous organs, but rarely involving the digestive system, especially the liver. Previously reported osteoclast-like giant cell carcinoma of the liver often coexists with sarcomatoid or hepatocellular carcinoma. Undifferentiated liver tumors with osteoclast-like giant cells (OGCs) are extremely rare. Due to its rarity, there is no consensus for diagnosis and treatment of undifferentiated liver tumors with OGCs. Definitive diagnosis comes from surgery, so there is often a long delay in diagnosis following the occurrence of symptoms. This case describes an extremely rare case of an undifferentiated liver tumor with OGCs in detail. It also summarizes the previously published cases based on liver tumors with OGCs from August 1980 to June 2021, providing extensive evidence to improve preoperative diagnosis and management options.
破骨细胞样巨细胞瘤（OGCT）是一种常见的骨肿瘤，偶尔在一些骨外器官中观察到，但很少累及消化系统，尤其是肝脏。先前报道的肝脏破骨细胞样巨细胞癌常与肉瘤样或肝细胞癌共存。具有破骨细胞样巨细胞（OGCs）的未分化肝肿瘤极为罕见。由于其罕见性，对于具有OGCs的未分化肝肿瘤的诊断和治疗尚无共识。明确诊断来自手术，因此症状出现后诊断往往会有很长时间的延迟。本病例详细描述了一例极为罕见的具有OGCs的未分化肝肿瘤。它还总结了1980年8月至2021年6月期间先前发表的基于具有OGCs的肝肿瘤的病例，为改善术前诊断和管理方案提供了广泛的证据。
