Wu Ying-Qi, Tong Tong
Department of Pharmacy, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China.
Front Pharmacol. 2023 Jan 10;13:1015098. doi: 10.3389/fphar.2022.1015098. eCollection 2022.
Curcumae Rhizoma is the dry rhizome coming from Curcuma longa L. which grow widely in tropical south and southwest Asia. It has been used to treat conditions such as dermatoses, infections, stress, and depression. Moreover, in China, Curcumae Rhizoma and its active constituents have been made into different pharmaceutical preparations. Growing evidence suggests that these preparations can exert antioxidant, anti-inflammatory, and anti-cancer effects, which may play crucial roles in the treatment of various diseases, including cancer, infectious-, autoimmune-, neurological-, and cardiovascular diseases, as well as diabetes. The anti-infective effect of Curcumae Rhizoma has become a popular field of research around the world, including for the treatment of COVID-19, influenza virus, hepatitis B virus, human immunodeficiency virus, and human papilloma virus, among others. In this paper, the basic characteristics of Curcumae Rhizoma and its active constituents are briefly introduced, and we also give an overview on their applications and mechanisms in infectious diseases.
姜黄是姜黄属植物姜黄的干燥根茎，姜黄在热带亚洲南部和西南部广泛种植。它已被用于治疗皮肤病、感染、压力和抑郁症等病症。此外，在中国，姜黄及其活性成分已被制成不同的药物制剂。越来越多的证据表明，这些制剂可以发挥抗氧化、抗炎和抗癌作用，这可能在治疗各种疾病中发挥关键作用，包括癌症、感染性疾病、自身免疫性疾病、神经疾病、心血管疾病以及糖尿病。姜黄的抗感染作用已成为世界各地一个热门的研究领域，包括用于治疗新型冠状病毒肺炎、流感病毒、乙型肝炎病毒、人类免疫缺陷病毒和人乳头瘤病毒等。本文简要介绍了姜黄及其活性成分的基本特性，并概述了它们在传染病中的应用及作用机制。
