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[后纵韧带肥厚所致脊髓病(HPLL):病例报告]

[Myelopathy caused by hypertrophy of the posterior longitudinal ligament (HPLL): case report].

作者信息

Kurata A, Tokiwa K, Kitahara I, Okada K, Mii K, Tachibana S, Ohwada T, Yada K

机构信息

Department of Neurosurgery, Kitasato University School of Medicine, Kanagawa, Japan.

出版信息

No Shinkei Geka. 1987 Jun;15(6):651-5.

PMID:3670537
Abstract

A case of myelopathy caused by hypertrophy of the posterior longitudinal ligament at the cervical spine is reported. A 71-year-old man was hospitalized with myelopathy with progressed during the last two months. Plain X-ray of the cervical spine revealed only mild spondylotic change. Myelography demonstrated completely blocked contrast medium at C4 to C5 vertebral height due to epidural mass. This epidural mass was localized ventral to the spinal cord from C3 to C5. CT scan revealed slightly high density area behind the vertebral body. On surgery, no evidence of disc fragment but only hypertrophied posterior longitudinal ligament which was removed was found to be a cause of cord compression. Excellent recovery of neurological symptoms after operation was obtained. On histological study, remarkable hypertrophy, edema, hyalinoid degeneration and a little calcification of the ligament was found, which did not show any evidence of new bone formation. HPLL was characterized by thickened and broad epidural mass in the ventral side of cervical cord with Hounsfield number of 90-156 on CT scan, which is not very easy to differentiate from metastatic epidural tumor. The cause of HPLL is not well elucidated, though, this may be a new category of compression myelopathy.

摘要

报告了一例因颈椎后纵韧带肥厚导致脊髓病的病例。一名71岁男性因脊髓病住院,病情在过去两个月中进展。颈椎X线平片仅显示轻度脊柱退变改变。脊髓造影显示在C4至C5椎体高度因硬膜外肿块导致造影剂完全阻塞。该硬膜外肿块位于C3至C5脊髓腹侧。CT扫描显示椎体后方有略高密度区。手术中,未发现椎间盘碎片证据,仅发现肥厚的后纵韧带,切除该韧带后发现是脊髓受压的原因。术后神经症状得到了显著恢复。组织学研究发现韧带显著肥厚、水肿、玻璃样变性及少许钙化,未显示任何新骨形成的证据。肥厚性颈椎后纵韧带的特征是在颈髓腹侧有增厚且广泛的硬膜外肿块,CT扫描时其Hounsfield值为90 - 156,这与转移性硬膜外肿瘤不太容易区分。虽然肥厚性颈椎后纵韧带的病因尚未完全阐明,但这可能是一种新的压迫性脊髓病类型。

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