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46 例鹦鹉热患者的临床特征。

Clinical features of psittacosis in 46 Chinese patients.

机构信息

Department of Respiratory Disease, Key Laboratory of Clinical Cancer Pharmacology and Toxicology Research of Zhejiang Province, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China.

Department of Pulmonary and Critical Care Medicine, The First Hospital of Longyan Affiliated to Fujian Medical University, Longyan, Fujian Province, China.

出版信息

Enferm Infecc Microbiol Clin (Engl Ed). 2023 Nov;41(9):545-548. doi: 10.1016/j.eimce.2022.05.016. Epub 2023 Jan 25.

Abstract

BACKGROUND

Psittacosis is a relatively uncommon cause of community-acquired pneumonia, often leading to diagnostic difficulty.

METHODS

A retrospective study was conducted on the clinical features of psittacosis patients in China. Forty-six cases of Chlamydophila psittaci infection with atypical pneumonia of varying severity in the last two years were described retrospectively.

RESULTS

Fever, relative bradycardia, and other systemic upsets were the main clinical presentation. The most common radiographic abnormality was segmental or lobar shadowing or consolidation. The total white cell counts were usually normal or slightly increased. The concentration of creatine kinase, C reactive protein, and lactic dehydrogenase increased, while albumin decreased remarkably. These cases exhibited good recovery after being treated with tetracycline or quinolone antibiotics.

CONCLUSION

These features may help differentiate psittacosis from other traditional bacterial pneumonia. However, they do not provide a definitive diagnosis. Psittacosis diagnosis must perform the whole-genome sequencing for Chlamydophila psittaci in respiratory, blood, or sputum specimens. Increased awareness of psittacosis can shorten diagnostic delays and improve patient outcomes.

摘要

背景

鹦鹉热是一种相对少见的社区获得性肺炎病因,常导致诊断困难。

方法

对过去两年中中国鹦鹉热衣原体感染不典型肺炎的 46 例病例进行了回顾性研究。

结果

发热、相对心动过缓和其他全身不适是主要的临床特征。最常见的放射学异常是节段性或肺叶阴影或实变。白细胞总数通常正常或略有增加。肌酸激酶、C 反应蛋白和乳酸脱氢酶浓度升高,而白蛋白显著降低。这些病例经四环素或喹诺酮类抗生素治疗后恢复良好。

结论

这些特征有助于将鹦鹉热与其他传统细菌性肺炎区分开来。然而,它们并不能提供明确的诊断。鹦鹉热的诊断必须对呼吸道、血液或痰标本中的鹦鹉热衣原体进行全基因组测序。提高对鹦鹉热的认识可以缩短诊断延误,改善患者的预后。

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