Liu Bowen, Yu Jingxuan, Fan Qiwei, Hao Fengwei, Wu Jinlong, Xiao Wen, Yu Fengyu, Ren Zhanbing
College of Physical Education, Shenzhen University, Shenzhen, China.
Department of Sports Medicine and Rehabilitation, Peking University Shenzhen Hospital, Shenzhen, China.
Front Neurol. 2023 Jan 11;13:1074521. doi: 10.3389/fneur.2022.1074521. eCollection 2022.
To investigate the effect of exercise on the walking economy (WE) of patients with chronic neurological conditions (CNCs) and to determine the type of physical activity that best improves the WE of patients with CNCs.
Four electronic databases were searched until December 2022 (Web of Science, PubMed, Cochrane, and CINAHL). Studies were screened using the following inclusion criteria: 1. randomized controlled or non-randomized controlled trials; 2. exercise interventions >4 weeks in duration; 3. patients aged ≥18 years with a diagnosis of CNCs. 4. walking economy of patients measured before and after the intervention. The PEDro scale was used to assess the methodological quality of the included studies.
Twenty-two studies met the inclusion criteria. Meta-analysis results showed that exercise significantly improved WE (g = -0.352, 95% CI, -0.625 to -0.078, = 0.012). Subgroup analysis revealed that patients who received exercise showed better WE compared with those who underwent no control intervention (g = -0.474, 95% CI, -0.636 to -0.311, < 0.001). However, exercise therapy did not show a significant improvement of WE compared with control groups (g = -0.192, 95% CI, -0.451 to 0.067, = 0.146). In addition, we found that endurance combined with resistance, high-intensity intermittent, and other training modalities resulted in better WE compared with the pre-intervention. Of these, interval training has the greatest effect on improving WE. In conclusion, exercise can improve WE in patients with CNCs. More randomized controlled trials are necessary for the future.
https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42022361455, identifier: CRD42022361455.
探讨运动对慢性神经疾病（CNC）患者步行经济性（WE）的影响，并确定最能改善CNC患者WE的身体活动类型。
检索了四个电子数据库直至2022年12月（科学网、PubMed、Cochrane和CINAHL）。使用以下纳入标准筛选研究：1. 随机对照或非随机对照试验；2. 运动干预持续时间>4周；3. 年龄≥18岁且诊断为CNC的患者。4. 在干预前后测量患者的步行经济性。使用PEDro量表评估纳入研究的方法学质量。
22项研究符合纳入标准。荟萃分析结果显示，运动显著改善了WE（g = -0.352，95% CI，-0.625至-0.078，P = 0.012）。亚组分析显示，接受运动的患者与未接受对照干预的患者相比，WE更好（g = -0.474，95% CI，-0.636至-0.311，P < 0.001）。然而，与对照组相比，运动疗法并未显示出WE的显著改善（g = -0.192，95% CI，-0.451至0.067，P = 0.146）。此外，我们发现，与干预前相比，耐力结合阻力、高强度间歇训练和其他训练方式导致更好的WE。其中，间歇训练对改善WE的效果最大。总之，运动可以改善CNC患者的WE。未来需要更多的随机对照试验。
https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42022361455，标识符：CRD42022361455。
