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通过抗菌药物管理优化两步诊断算法结果的解读

Optimizing the interpretation of two-step diagnostic algorithm results through antimicrobial stewardship.

作者信息

Lowe Christopher F, Shakeraneh Shayan, Lee Colin, Sharma Azra, Leung Victor

机构信息

Pathology and Laboratory Medicine, Providence Health Care, Vancouver, British Columbia, Canada.

Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.

出版信息

Antimicrob Steward Healthc Epidemiol. 2022 Dec 15;2(1):e201. doi: 10.1017/ash.2022.350. eCollection 2022.

DOI:10.1017/ash.2022.350
PMID:36712476
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9879867/
Abstract

Over a 4-year period, the antimicrobial stewardship team reviewed all positive (PCR+/Tox+) and indeterminate (PCR+/Tox-) cases with the most responsible physician for classification of patients as infection or colonization. Among 501 indeterminate samples, 213 (43%) were considered to be clinical infection, suggesting the need for ongoing clinical assessment of indeterminates.

摘要

在4年的时间里,抗菌药物管理团队与责任最大的医生一起审查了所有阳性(PCR+/Tox+)和不确定(PCR+/Tox-)病例,以将患者分类为感染或定植。在501份不确定样本中,213份(43%)被认为是临床感染,这表明需要对不确定病例进行持续的临床评估。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a472/9879867/81bb670c1144/S2732494X22003503_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a472/9879867/81bb670c1144/S2732494X22003503_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a472/9879867/81bb670c1144/S2732494X22003503_fig1.jpg

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本文引用的文献

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J Clin Microbiol. 2022 Jun 15;60(6):e0218721. doi: 10.1128/jcm.02187-21. Epub 2022 May 25.
2
The Impact of Infection Versus Colonization on Environmental Contamination in Hospitalized Patients With Diarrhea.感染与定植对腹泻住院患者环境污染的影响
Open Forum Infect Dis. 2022 Feb 9;9(4):ofac069. doi: 10.1093/ofid/ofac069. eCollection 2022 Apr.
3
Use of diagnostic and antimicrobial stewardship practices to improve testing among SHEA Research Network hospitals.
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Infect Control Hosp Epidemiol. 2022 Jul;43(7):930-934. doi: 10.1017/ice.2021.133. Epub 2021 Aug 11.
4
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5
Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA).临床实践指南:成人和儿童艰难梭菌感染:美国传染病学会(IDSA)和美国医疗保健流行病学学会(SHEA) 2017 年更新。
Clin Infect Dis. 2018 Mar 19;66(7):e1-e48. doi: 10.1093/cid/cix1085.
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