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用于增加牙种植体周围角化黏膜宽度的覆盖富血小板纤维蛋白膜与游离龈移植术:一项半口随机对照临床研究。

Onlay platelet-rich fibrin membrane versus free gingival graft in increasing the width of keratinized mucosa around dental implants: A split-mouth randomized clinical study.

作者信息

Al-Diasty Zeinab, El-Meadawy Samah, Salem Ahmed S, Mowafey Bassant

机构信息

Department of Periodontology, Faculty of Dentistry, Mansoura University, Egypt.

Department of Oral Medicine and Periodontology, Faculty of Dentistry, Mansoura University, Egypt.

出版信息

J Adv Periodontol Implant Dent. 2022 Aug 24;14(2):53-61. doi: 10.34172/japid.2022.013. eCollection 2022.

DOI:10.34172/japid.2022.013
PMID:36714088
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9871183/
Abstract

This study aimed to compare the use of the platelet-rich fibrin membrane (PRF) versus the free gingival graft (FGG) during the second stage of the dental implant to increase the amount of keratinized mucosa around dental implants. Fifteen patients with bilaterally missing teeth and deficient width of the keratinized mucosa (KM) were recruited for a spit-mouth randomized controlled trial. After implant placement on the control sides, onlay FGG was used, whereas, on the other side (study side), onlay PRF membranes were applied to augment the KM. One month and three months after augmentation, the increase in keratinized mucosa width, bone level around the implants, and soft tissue health were evaluated and compared. The shrinkage percentage was also calculated for both grafts. There was a significant increase in the width of KM in the FGG and PRF groups; however, it was observed that FFG resulted in significantly better results than PRF, with no significant difference in peri-implant soft tissue health or bone level. Within the limitations of this study, it was concluded that the onlay PRF membrane could increase the keratinized mucosa width around dental implants with the advantages of a lower surgical time and less postoperative discomfort and pain for the patients in comparison to the FGG. However, FGG had a significantly higher ability to augment and increase keratinized mucosa around dental implants.

摘要

本研究旨在比较在牙种植二期使用富血小板纤维蛋白膜(PRF)与游离龈瓣移植(FGG),以增加牙种植体周围角化黏膜的量。招募了15例双侧牙齿缺失且角化黏膜(KM)宽度不足的患者,进行了一项分口随机对照试验。在对照侧植入种植体后,使用覆盖式FGG,而在另一侧(研究侧),应用覆盖式PRF膜来增加KM。在增宽术后1个月和3个月,评估并比较角化黏膜宽度的增加、种植体周围的骨水平以及软组织健康状况。还计算了两种移植物的收缩率。FGG组和PRF组的KM宽度均有显著增加;然而,观察到FGG的效果明显优于PRF,种植体周围软组织健康状况或骨水平无显著差异。在本研究的局限性范围内,得出的结论是,与FGG相比,覆盖式PRF膜可增加牙种植体周围角化黏膜的宽度,具有手术时间更短、患者术后不适和疼痛更少的优点。然而,FGG在增加牙种植体周围角化黏膜方面具有显著更高的能力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f8b/9871183/1cf0980b2cc8/japid-14-53-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f8b/9871183/daa758d52350/japid-14-53-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f8b/9871183/a47682afe410/japid-14-53-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f8b/9871183/1cf0980b2cc8/japid-14-53-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f8b/9871183/daa758d52350/japid-14-53-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f8b/9871183/a47682afe410/japid-14-53-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f8b/9871183/1cf0980b2cc8/japid-14-53-g003.jpg

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本文引用的文献

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Int J Environ Res Public Health. 2019 Jul 18;16(14):2570. doi: 10.3390/ijerph16142570.
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L-PRF for increasing the width of keratinized mucosa around implants: A split-mouth, randomized, controlled pilot clinical trial.富血小板纤维蛋白(L-PRF)增加种植体周围角化黏膜宽度的研究:一项随机、对照、分侧口腔临床试验。
J Periodontal Res. 2018 Oct;53(5):793-800. doi: 10.1111/jre.12568. Epub 2018 Jun 2.
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Free gingival grafts for implants exhibiting lack of keratinized mucosa: a prospective controlled randomized clinical study.
富血小板纤维蛋白能否改善种植体周围软组织的预后?一项系统评价。
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