Wu Jinzhi, Yang Fan, Ma Xinlei, Lin Jin, Chen Weiqian
Division of Rheumatology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Front Med (Lausanne). 2023 Jan 12;9:1083879. doi: 10.3389/fmed.2022.1083879. eCollection 2022.
Rheumatoid arthritis is a chronic autoimmune disease that mainly affects the facet joints. Elderly-onset rheumatoid arthritis appears to exhibit symptoms similar to those of polymyalgia rheumatica, characterized by morning stiffness and pain in the shoulder and hip joints. Both diseases develop in the elderly, and it is sometimes challenging to distinguish them. Here, we identify the differences in pathogenesis between elderly-onset rheumatoid arthritis and polymyalgia rheumatica to assist with a clear differential diagnosis and effective early intervention.
类风湿性关节炎是一种主要影响小关节的慢性自身免疫性疾病。老年发病的类风湿性关节炎似乎表现出与风湿性多肌痛相似的症状，其特征为晨僵以及肩部和髋关节疼痛。这两种疾病都在老年人中发病，有时很难区分它们。在此，我们确定老年发病的类风湿性关节炎和风湿性多肌痛在发病机制上的差异，以协助进行明确的鉴别诊断和有效的早期干预。
