Naser Abdallah Y, Al-Shehri Hassan
Department of Applied Pharmaceutical Sciences and Clinical Pharmacy, Faculty of Pharmacy, Isra University, Amman, Jordan.
Department of Pediatrics, College of Medicine, Imam Mohammad Ibn Saud Islamic University, Riyadh, Saudi Arabia.
J Multidiscip Healthc. 2023 Jan 22;16:199-207. doi: 10.2147/JMDH.S396406. eCollection 2023.
The aim of this study was to look into the rates of perinatal admissions for respiratory, cardiac, and cardiovascular diseases in England.
This ecological study was conducted in England. The Hospital Episode Statistics (HES) database in England provided the study with the publicly accessible data. The data set for this study was considered between April 01, 2012 and April 01, 2020. The HES database contains information on patients' admissions to hospitals, notably for those hospitalised with perinatal cardiovascular and respiratory diseases. We used the chi-squared test to assess the difference between the hospital admission rates between 2012 and 2020.
An increase of 15.6% was observed in hospital admissions rate during the study period [from 10,940.37 (95% CI 10,865.99-11,014.75) in 2012 to 12,649.00 (95% CI 12,565.03-12,732.98) in 2020 per 100,000 people, p<0.05]. Intrauterine hypoxia, chest congestion and breathing-related respiratory distress of newborns, and other perinatal respiratory disorders accounted for 35.5%, 29.8%, and 21.3%, respectively. Males contributed for more than half of them (56.7%). The rate of hospital admission among males increased by 15.1% [from 12,227.79 (95% CI 12,118.83-12,336.74) in 2012 to 14,074.77 (95% CI 13,952.11-14,197.43) in 2020 per 100,000 persons, p<0.05]. The rate of hospital admission among females increased by 17.4% [from 9,646.15 (95% CI 9,545.31-9,747.00) in 2012 to 11,324.20 (95% CI 11,209.47-11,438.92) in 2020 per 100,000 persons, p<0.05].
The study's findings show that the most common causes of hospital admissions for respiratory and cardiovascular disorders were intrauterine hypoxia, neonatal respiratory distress, and other perinatal respiratory issues, which were detected particularly during the perinatal period. Further research is warranted to identify risk factors of hospital admissions for respiratory and cardiovascular disorders during the perinatal period.
本研究旨在调查英格兰围产期因呼吸系统、心脏和心血管疾病的住院率。
这项生态学研究在英格兰进行。英格兰的医院事件统计（HES）数据库为该研究提供了可公开获取的数据。本研究的数据集涵盖2012年4月1日至2020年4月1日期间。HES数据库包含患者住院信息，尤其是那些因围产期心血管和呼吸系统疾病住院的患者信息。我们使用卡方检验来评估2012年至2020年期间住院率的差异。
在研究期间，观察到住院率增加了15.6%[从2012年的每10万人中10,940.37例（95%置信区间10,865.99 - 11,014.75）增加到2020年的每10万人中12,649.00例（95%置信区间12,565.03 - 12,732.98），p<0.05]。宫内缺氧、新生儿胸部充血和与呼吸相关的呼吸窘迫以及其他围产期呼吸系统疾病分别占35.5%、29.8%和21.3%。其中男性占比超过一半（56.7%）。男性的住院率增加了15.1%[从2012年的每10万人中12,227.79例（95%置信区间12,118.83 - 12,336.74）增加到2020年的每10万人中14,074.77例（95%置信区间13,952.11 - 14,197.43），p<0.05]。女性的住院率增加了17.4%[从2012年的每10万人中9,646.15例（95%置信区间9,545.31 - 9,747.00）增加到2020年的每10万人中11,324.20例（95%置信区间11,209.47 - 11,438.92），p<0.05]。
该研究结果表明，呼吸系统和心血管疾病住院的最常见原因是宫内缺氧、新生儿呼吸窘迫和其他围产期呼吸问题，这些问题在围产期尤其容易被发现。有必要进一步开展研究以确定围产期呼吸系统和心血管疾病住院的风险因素。
