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双向动脉导管未闭或室间隔缺损犬在药物治疗后出现反分流进展和左向右分流改善的超声心动图变化:两例报告。

Echocardiographic changes in the progress of reverse shunt and improvement to left-to-right shunt after medical treatment in dogs with bidirectional patent ductus arteriosus or ventricular septal defect: A report of two cases.

机构信息

Department of Veterinary Medical Imaging, College of Veterinary Medicine, Jeonbuk National University, Iksan, South Korea.

Bundang Leaders Animal Medical Center, Seongnam, South Korea.

出版信息

Vet Med Sci. 2023 May;9(3):1044-1052. doi: 10.1002/vms3.1081. Epub 2023 Jan 30.

DOI:10.1002/vms3.1081
PMID:36716384
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10188055/
Abstract

Two Maltese dogs were referred for evaluation of a congenital heart disease: one was diagnosed with patent ductus arteriosus and the other was diagnosed with a ventricular septal defect. The PDA patient was diagnosed with congenital heart disease 2 weeks ago and the VSD patient about 11 months ago at another hospital. Echocardiographic findings revealed a bidirectional shunt condition, and the dogs were treated with medical management using sildenafil and oxygen inhalation. After medical management, the dogs returned to clinically normal conditions, and echocardiographic findings revealed a return to left-to-right shunt tendency. These dogs had no clinical signs associated with heart disease 3 years after treatment. This case report describes changes in echocardiography findings according to the progression of the reverse shunt and the possibility of improvement to a left-to-right shunt after medical treatment.

摘要

两只马耳他犬因先天性心脏病被转诊进行评估

一只被诊断为动脉导管未闭,另一只被诊断为室间隔缺损。PDA 患者在 2 周前被诊断出患有先天性心脏病,而 VSD 患者在 11 个月前在另一家医院被诊断出患有该病。超声心动图检查结果显示双向分流情况,这些犬使用西地那非和吸氧进行了药物治疗。在药物治疗后,这些犬的临床状况恢复正常,超声心动图检查结果显示其分流方向恢复为左向右。治疗 3 年后,这些犬没有与心脏病相关的临床症状。本病例报告描述了随着反向分流的进展,超声心动图检查结果的变化以及药物治疗后可能改善为左向右分流的情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a7f6/10188055/30162635d2e6/VMS3-9-1044-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a7f6/10188055/0b4c25b14d8f/VMS3-9-1044-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a7f6/10188055/f9b98c822bfd/VMS3-9-1044-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a7f6/10188055/6d8cef38f856/VMS3-9-1044-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a7f6/10188055/30162635d2e6/VMS3-9-1044-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a7f6/10188055/0b4c25b14d8f/VMS3-9-1044-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a7f6/10188055/f9b98c822bfd/VMS3-9-1044-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a7f6/10188055/6d8cef38f856/VMS3-9-1044-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a7f6/10188055/30162635d2e6/VMS3-9-1044-g005.jpg

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本文引用的文献

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ACVIM consensus statement guidelines for the diagnosis, classification, treatment, and monitoring of pulmonary hypertension in dogs.ACVIM 共识声明指南:犬肺动脉高压的诊断、分类、治疗和监测。
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Eisenmenger syndrome.
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Pentoxifylline as adjunct therapy to long-term clinical management of a right-to-left patent ductus arteriosus.己酮可可碱作为右向左分流型动脉导管未闭长期临床管理的辅助治疗方法。
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Signalment, clinical features, echocardiographic findings, and outcome of dogs and cats with ventricular septal defects: 109 cases (1992-2013).1992年至2013年109例患有室间隔缺损的犬猫的信号、临床特征、超声心动图表现及预后
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Differential cyanosis and undiagnosed eisenmenger's syndrome: The importance of pulse oximetry.差异性发绀与未确诊的艾森曼格综合征:脉搏血氧饱和度测定的重要性。
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