Research Department of Reproductive Health, UCL Institute for Women's Health, London, UK
Research Department of Reproductive Health, UCL Institute for Women's Health, London, UK.
BMJ Sex Reprod Health. 2023 Jul;49(3):167-175. doi: 10.1136/bmjsrh-2022-201750. Epub 2023 Jan 30.
Clinicians and women of reproductive age would benefit from a reliable way to identify who is likely to become pregnant in the next year, in order to direct health advice. The 14-item Desire to Avoid Pregnancy (DAP) scale is predictive of pregnancy; this paper compares it with other ways of assessing pregnancy preferences to shortlist options for clinical implementation.
A cohort of 994 UK women of reproductive age completed the DAP and other questions about pregnancy preferences, including the Attitude towards Potential Pregnancy Scale (APPS), at baseline and reported on pregnancies quarterly for a year. For each question, DAP item and combinations of DAP items, we examined the predictive ability, sensitivity, specificity, area under the receiver operating curve (AUROC), and positive and negative predictive values.
The AUROCs and predictive ability of the APPS and DAP single items were weaker than the full DAP, though all except one had acceptable AUROCs (>0.7). The most predictive individual DAP item was 'It would be a good thing for me if I became pregnant in the next 3 months', where women who strongly agreed had a 66.7% chance of pregnancy within 12 months and the AUROC was acceptable (0.77).
We recommend exploring the acceptability to women and healthcare professionals of asking a single DAP item ('It would be a good thing for me if I became pregnant in the next 3 months'), possibly in combination with additional DAP items. This will help to guide service provision to support reproductive preferences.
为了提供有针对性的健康建议,临床医生和育龄女性都希望有一种可靠的方法来识别哪些人可能在未来一年内怀孕。14 项避免怀孕意愿量表(DAP)可以预测怀孕;本文将其与其他评估怀孕意愿的方法进行比较,以筛选出可供临床实施的选项。
一组 994 名英国育龄妇女在基线时完成了 DAP 及其他关于怀孕意愿的问题,包括潜在怀孕态度量表(APPS),并在一年内每季度报告怀孕情况。对于每个问题、DAP 项目和 DAP 项目组合,我们都检查了预测能力、敏感性、特异性、受试者工作特征曲线下面积(AUROC)以及阳性和阴性预测值。
APPS 和 DAP 单项的 AUROC 和预测能力均弱于完整的 DAP,尽管除一项外,其余的 AUROC 均>0.7,均具有可接受的预测能力。最具预测性的 DAP 单项是“如果我在接下来的 3 个月内怀孕,对我来说将是一件好事”,强烈同意的女性在 12 个月内怀孕的可能性为 66.7%,AUROC 可接受(0.77)。
我们建议探索询问 DAP 单项(“如果我在接下来的 3 个月内怀孕,对我来说将是一件好事”)的可接受性,可能还需要结合其他 DAP 项目,这将有助于指导服务提供,以支持生殖偏好。