Szkoda Lawia, Szopa Andrzej, Kwiecień-Czerwieniec Ilona, Siwiec Andrzej, Domagalska-Szopa Małgorzata
Department of Physiotherapy, Medical University of Silesia in Katowice, Katowice, Poland.
John Paul II Pediatric Center in Sosnowiec, Sosnowiec, Poland.
Int J Gen Med. 2023 Jan 24;16:281-291. doi: 10.2147/IJGM.S393484. eCollection 2023.
The purpose of this study was to identify quantitative (BMI z-score and BMI percentile) and qualitative (BC) differences between high functioning outpatient children with CP (GMFCS levels I/II) vs TD children, using BIA. We hypothesized that: 1) BMI z-score and BMI percentile will be lower in children with CP compared with their TD peers; and 2) body components (BC) directly associated with muscle mass (including fat free mass (FFM%) and skeletal muscle mass (SMM) and predicted muscle mass (PMM)) in children with CP will be lower than in their TD peers.
Ninety children with CP (GMFCS levels I/II) aged 8-16 years were enrolled in this study. Due to the fact that there is lack of normative values of particular body components in the pediatric population, ninety typically developing (TD) peers were used as references. The examination consisted of two parts: 1) the height measurement and 2) body composition assessments, both using the bioelectric impedance analysis (BIA).
Average values for height, weight, BMI z-score, and BMI percentile in children with CP were significantly statistically lower than in the reference group. BC's directly associated with muscle mass (including FFM%, SMM, and PMM) in children with CP were lower than those in their TD peers.
Altered body compositions were evident in children with CP.
本研究旨在通过生物电阻抗分析(BIA),确定高功能门诊脑瘫儿童(GMFCS I/II级)与发育正常儿童在定量指标(BMI z评分和BMI百分位数)和定性指标(身体成分)方面的差异。我们假设:1)脑瘫儿童的BMI z评分和BMI百分位数低于发育正常的同龄人;2)脑瘫儿童中与肌肉量直接相关的身体成分(包括去脂体重百分比(FFM%)、骨骼肌量(SMM)和预测肌肉量(PMM))低于发育正常的同龄人。
本研究纳入了90名8至16岁的脑瘫儿童(GMFCS I/II级)。由于儿科人群中特定身体成分缺乏标准值,因此将90名发育正常的同龄人作为对照。检查包括两个部分:1)身高测量;2)身体成分评估,均采用生物电阻抗分析(BIA)。
脑瘫儿童的身高、体重、BMI z评分和BMI百分位数的平均值在统计学上显著低于对照组。脑瘫儿童中与肌肉量直接相关的身体成分(包括FFM%、SMM和PMM)低于发育正常的同龄人。
脑瘫儿童存在明显的身体成分改变。