Wu Tingyi, Wang Yuexin, Yu Jiazhi, Ren Xiaotong, Li Yuanting, Qiu Weiqiang, Li Xuemin
Department of Ophthalmology, Peking University Third Hospital, 49 North Garden Road, Haidian District, Beijing, 100191, People's Republic of China.
Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Peking University Third Hospital, Beijing, People's Republic of China.
Eye Vis (Lond). 2023 Feb 1;10(1):5. doi: 10.1186/s40662-022-00323-0.
The aim of the study was to compare the dynamic defocus curve on patients post-implantation of the extended depth-of-focus (EDOF) and monofocal intraocular lens (IOL).
A total of 62 age-related cataract patients receiving phacoemulsification with implantation of TECNIS Symfony (ZXR00) or monofocal IOLs were enrolled. The binocular static and dynamic defocus curves with corrected distance visual acuity were evaluated at one month postoperatively.
The ZXR00 group achieved significantly better intermediate (P = 0.044) and near (P = 0.017) visual acuity (VA) than the monofocal group. Two groups had similar uncorrected and corrected distance VA (P > 0.05, respectively). The dynamic defocus curve revealed a smoother decline from 0.0 D to - 2.0 D in the ZXR00 group. Defocused dynamic VA in the ZXR00 group was significantly better (P < 0.05) except at 0.0 D (P = 0.724) and - 0.5 D (P = 0.176). The area under the curve (P = 0.002) and corrected dynamic vision accommodation (P = 0.001) derived from the dynamic defocus curves were better in the ZXR00 group. A positive correlation was observed between defocused dynamic and static VA in both groups (P < 0.001). Multiple linear regression analysis indicated that defocused static VA and corrected dynamic vision accommodation were significant influential factors for the defocused dynamic VA from - 1.0 D to - 3.0 D (P < 0.05).
The EDOF IOL provided similar distance vision, better intermediate and near vision, and a better overall dynamic defocus curve than the monofocal IOL. The dynamic defocus curve may be comprehensively applied to evaluate the all-distance dynamic visual performance post-cataract surgery.
本研究旨在比较植入扩展景深（EDOF）人工晶状体（IOL）和单焦点IOL的患者的动态离焦曲线。
共纳入62例接受超声乳化白内障吸除术并植入TECNIS Symfony（ZXR00）或单焦点IOL的年龄相关性白内障患者。术后1个月评估双眼静态和动态离焦曲线及矫正远视力。
ZXR00组在中视力（P = 0.044）和近视力（P = 0.017）方面显著优于单焦点组。两组的未矫正和矫正远视力相似（P均> 0.05）。动态离焦曲线显示ZXR00组从0.0 D到 -2.0 D的下降更为平滑。ZXR00组除0.0 D（P = 0.724）和 -0.5 D（P = 0.176）外，离焦动态视力显著更好（P < 0.05）。ZXR00组动态离焦曲线得出的曲线下面积（P = 0.002）和矫正动态视觉调节（P = 0.001）更好。两组离焦动态视力与静态视力之间均呈正相关（P < 0.001）。多元线性回归分析表明，离焦静态视力和矫正动态视觉调节是 -1.0 D至 -3.0 D离焦动态视力的显著影响因素（P < 0.05）。
与单焦点IOL相比，EDOF IOL提供了相似的远视力、更好的中视力和近视力以及更好的整体动态离焦曲线。动态离焦曲线可综合应用于评估白内障手术后的全距离动态视觉性能。
