Morante-Palacios Octavio
Epigenetics and Immune Disease Group, Josep Carreras Research Institute (IJC), Barcelona, Spain.
Germans Trias i Pujol Research Institute (IGTP), Barcelona, Spain.
Methods Mol Biol. 2023;2624:7-18. doi: 10.1007/978-1-0716-2962-8_2.
Arrays provide a cost-effective platform for the analysis of human DNA methylation. ShinyÉPICo is an interactive, web-based, and graphical tool that allows the user to analyze Illumina DNA methylation arrays (450 k and EPIC), from the user's own computer or from a server. This tool covers the analysis entirely, from the raw data input to the final list of differentially methylated positions or regions. Here, we describe the steps of the analysis, the different parameters available, and useful information to understand and select the best options in each step.
阵列提供了一个经济高效的人类DNA甲基化分析平台。ShinyÉPICo是一个交互式的、基于网络的图形工具，允许用户从自己的计算机或服务器上分析Illumina DNA甲基化阵列（450k和EPIC）。该工具涵盖了从原始数据输入到差异甲基化位点或区域的最终列表的整个分析过程。在这里，我们描述了分析步骤、可用的不同参数，以及在每个步骤中理解和选择最佳选项的有用信息。
