Institute of Goats and Sheep Science, Nanjing Agricultural University, No. 1 Weigang, Nanjing, Jiangsu 210095, PR China.
J Appl Microbiol. 2023 Feb 16;134(2). doi: 10.1093/jambio/lxac079.
This trial was performed to investigate the effects of combined feeding of Candida utilis CICC 31170, Bacillus coagulans R11, and Lactobacillus acidophilus NCFM and a multi-enzyme complex on the growth performance, immune parameters, feed digestibility, and rumen microbiota of weaned goats.
Thirty weaned goats were randomly divided into CON, PRB, and COB groups and fed different diets. End weight and ADG increased significantly in the PRB and COB groups (P < 0.05), and ADFI increased significantly in COB (P < 0.05). On day 80, there was a significant increase in IL-10 content in PRB and COB compared to the CON (P < 0.05). Highly significant increases in rumen papilla width, epithelial cell thickness, stratum spinosum+basale thickness, and stratum corneum thickness were found in PRB and COB (P < 0.05). COB group significantly increased the gene expression of HMGCL and MCT1 in rumen epithelium (P < 0.001). The COB group had the tendency to increase the feed digestibility of dry matter and crude fat compared with the CON group (P < 0.10). The abundance of Prevotellaceae_unclassified was significantly higher in PRB (P < 0.05), and the abundance of Fibrobacteres was significantly higher in COB in comparison to those in CON (P < 0.05).
The results indicate that the dietary potential probiotics and enzymes complex could modulate the growth performance, immunity, feed digestibility, and rumen microbiota in weaned goats.
本试验旨在研究产朊假丝酵母 CICC31170、凝结芽孢杆菌 R11 和嗜酸乳杆菌 NCFM 与复合酶联合喂养对断奶山羊生长性能、免疫参数、饲料消化率和瘤胃微生物区系的影响。
30 只断奶山羊随机分为 CON、PRB 和 COB 组，并饲喂不同的日粮。PRB 和 COB 组的末重和 ADG 显著增加（P < 0.05），COB 组的 ADFI 显著增加（P < 0.05）。第 80 天，PRB 和 COB 组的 IL-10 含量显著高于 CON 组（P < 0.05）。PRB 和 COB 组的瘤胃乳头宽度、上皮细胞厚度、棘状层+基底层厚度和角质层厚度均显著增加（P < 0.05）。COB 组的 HMGCL 和 MCT1 基因在瘤胃上皮中的表达显著增加（P < 0.001）。与 CON 组相比，COB 组的干物质和粗脂肪的饲料消化率有增加的趋势（P < 0.10）。PRB 组普雷沃氏菌科未分类的丰度显著升高（P < 0.05），COB 组纤维杆菌丰度显著高于 CON 组（P < 0.05）。
结果表明，日粮潜在益生菌和复合酶可以调节断奶山羊的生长性能、免疫力、饲料消化率和瘤胃微生物区系。
