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空气污染与儿童哮喘。

Air pollution and childhood asthma.

作者信息

Mukharesh Lana, Phipatanakul Wanda, Gaffin Jonathan M

机构信息

Division of Pulmonary Medicine, Boston Children's Hospital.

Harvard Medical School.

出版信息

Curr Opin Allergy Clin Immunol. 2023 Apr 1;23(2):100-110. doi: 10.1097/ACI.0000000000000881. Epub 2022 Nov 24.

DOI:10.1097/ACI.0000000000000881
PMID:36730122
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11920647/
Abstract

PURPOSE OF REVIEW

Asthma is the most common chronic disease of childhood. Environmental exposures, such as allergens and pollutants, are ubiquitous factors associated with asthma development and asthma morbidity. In this review, we highlight the most recent studies relevant to childhood asthma risk, onset, and exacerbation related to air pollution exposure.

RECENT FINDINGS

In this article, we review current research that has been published between 2021 and 2022, demonstrating the effects of early-life exposure to key air pollutants (e.g., particulate matter (PM), nitrogen dioxide (NO 2 ), sulfur dioxide (SO 2 ) and ground-level ozone (O 3 ), environmental tobacco smoke, radon, and volatile organic compounds (VOC) on respiratory health.

SUMMARY

Air pollution continues to be a global burden with serious consequences related to respiratory health. Interventions aimed at reducing air pollution in the environment must be achieved in an effort to improve asthma outcomes and pediatric health.

摘要

综述目的

哮喘是儿童最常见的慢性疾病。环境暴露,如过敏原和污染物,是与哮喘发生及哮喘发病率相关的普遍因素。在本综述中,我们重点介绍了与空气污染暴露相关的儿童哮喘风险、发病及加重的最新研究。

最新发现

在本文中,我们回顾了2021年至2022年期间发表的当前研究,这些研究表明生命早期暴露于关键空气污染物(如颗粒物(PM)、二氧化氮(NO₂)、二氧化硫(SO₂)、地面臭氧(O₃)、环境烟草烟雾、氡和挥发性有机化合物(VOC))对呼吸健康的影响。

总结

空气污染仍然是一个全球负担,对呼吸健康有严重影响。必须采取旨在减少环境空气污染的干预措施,以改善哮喘结局和儿童健康。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65d0/11920647/4eab0f9eccee/nihms-2064921-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65d0/11920647/4eab0f9eccee/nihms-2064921-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65d0/11920647/4eab0f9eccee/nihms-2064921-f0001.jpg

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Size-segregated particle number concentrations and outpatient-department visits for pediatric respiratory diseases in Shanghai, China.中国上海按粒径分段的颗粒物数浓度与儿科呼吸道疾病门急诊就诊人次。
Ecotoxicol Environ Saf. 2022 Sep 15;243:113998. doi: 10.1016/j.ecoenv.2022.113998. Epub 2022 Aug 31.
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Interaction effect of prenatal and postnatal exposure to ambient air pollution and temperature on childhood asthma.
气候变化相关环境危害导致的免疫介导疾病:缓解与适应
Front Sci. 2024;2. doi: 10.3389/fsci.2024.1279192. Epub 2024 Apr 3.
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Recommendations for Clinicians to Combat Environmental Disparities in Pediatric Asthma: A Review.临床医生应对儿童哮喘环境差异的建议:综述
Chest. 2024 Dec;166(6):1309-1318. doi: 10.1016/j.chest.2024.07.143. Epub 2024 Jul 24.
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Environmental Interventions for Preventing Atopic Diseases.环境干预预防特应性疾病。
Curr Allergy Asthma Rep. 2024 May;24(5):233-251. doi: 10.1007/s11882-024-01141-1. Epub 2024 Mar 16.
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Asthma prevalence based on the Baidu index and China's Health Statistical Yearbook from 2011 to 2020 in China.基于 2011 年至 2020 年百度指数和中国卫生统计年鉴的中国哮喘患病率。
Front Public Health. 2023 Oct 4;11:1221852. doi: 10.3389/fpubh.2023.1221852. eCollection 2023.
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Environ Int. 2022 Sep;167:107456. doi: 10.1016/j.envint.2022.107456. Epub 2022 Aug 6.
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