空气污染与儿童哮喘。
Air pollution and childhood asthma.
作者信息
Mukharesh Lana, Phipatanakul Wanda, Gaffin Jonathan M
机构信息
Division of Pulmonary Medicine, Boston Children's Hospital.
Harvard Medical School.
出版信息
Curr Opin Allergy Clin Immunol. 2023 Apr 1;23(2):100-110. doi: 10.1097/ACI.0000000000000881. Epub 2022 Nov 24.
Abstract
PURPOSE OF REVIEW
Asthma is the most common chronic disease of childhood. Environmental exposures, such as allergens and pollutants, are ubiquitous factors associated with asthma development and asthma morbidity. In this review, we highlight the most recent studies relevant to childhood asthma risk, onset, and exacerbation related to air pollution exposure.
RECENT FINDINGS
In this article, we review current research that has been published between 2021 and 2022, demonstrating the effects of early-life exposure to key air pollutants (e.g., particulate matter (PM), nitrogen dioxide (NO 2 ), sulfur dioxide (SO 2 ) and ground-level ozone (O 3 ), environmental tobacco smoke, radon, and volatile organic compounds (VOC) on respiratory health.
SUMMARY
Air pollution continues to be a global burden with serious consequences related to respiratory health. Interventions aimed at reducing air pollution in the environment must be achieved in an effort to improve asthma outcomes and pediatric health.
摘要
综述目的
哮喘是儿童最常见的慢性疾病。环境暴露，如过敏原和污染物，是与哮喘发生及哮喘发病率相关的普遍因素。在本综述中，我们重点介绍了与空气污染暴露相关的儿童哮喘风险、发病及加重的最新研究。
最新发现
在本文中，我们回顾了2021年至2022年期间发表的当前研究，这些研究表明生命早期暴露于关键空气污染物（如颗粒物（PM）、二氧化氮（NO₂）、二氧化硫（SO₂）、地面臭氧（O₃）、环境烟草烟雾、氡和挥发性有机化合物（VOC））对呼吸健康的影响。
总结
空气污染仍然是一个全球负担，对呼吸健康有严重影响。必须采取旨在减少环境空气污染的干预措施，以改善哮喘结局和儿童健康。
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