Firat University, Faculty of Engineering, Computer Engineering, 23119, Elazig, Turkey.
Firat University, Faculty of Engineering, Software Engineering, 23119, Elazig, Turkey.
Comput Biol Med. 2023 Mar;154:106574. doi: 10.1016/j.compbiomed.2023.106574. Epub 2023 Jan 23.
Cervical cancer is a common disease in women, affecting their lives negatively and often resulting in death. Pap-smear tests are preferred by doctors as the primary tool in the early diagnosis and treatment of the disease. Physicians can be facilitated in the detection of five different categories of cervical cancer and similar cellular disease cases with the Pap-smear image retrieval technology. In this study, an algorithm for retrieval of cervical cancer images using hash coding with a Convolutional Neural Network (CNN) has been implemented. A sensitive deep hashing method combining interpretable mask generation and rotation invariance is proposed for cervical cancer detection. The distinctive features of cervical cancer cells with complex morphological features are focused on with the proposed hybrid dilated convolution spatial attention module and insignificant features are eliminated. Moreover, the loss function of Cauchy rotation invariance in terms of cervical cancer cell target is presented. In this way, the differences in the input samples are revealed, allowing the CNN to learn from different angles and achieve certain rotation invariance. The versatility and performance of the proposed method, as well as the efficiency of the loss function, have been tested on the SIPaKMeD and Mendeley LBC datasets consisting of cervical cancer images. In the experimental results obtained, it is shown that the proposed spatial attention module and rotational invariance deep hashing network generate high performance in cervical cancer image retrieval problems.
宫颈癌是一种常见的女性疾病,对她们的生活产生负面影响,常常导致死亡。巴氏涂片检查是医生首选的疾病早期诊断和治疗工具。医生可以使用巴氏涂片图像检索技术,方便地检测到五类不同的宫颈癌和类似的细胞疾病病例。在这项研究中,我们实现了一种使用哈希编码和卷积神经网络(CNN)的宫颈癌图像检索算法。我们提出了一种敏感的深度哈希方法,结合可解释的掩模生成和旋转不变性,用于宫颈癌检测。该方法专注于具有复杂形态特征的宫颈癌细胞的独特特征,并消除了不显著的特征。此外,我们还提出了一种基于宫颈癌细胞目标的 Cauchy 旋转不变性损失函数。通过这种方式,揭示了输入样本的差异,使 CNN 能够从不同角度学习,实现一定的旋转不变性。我们在包含宫颈癌图像的 SIPaKMeD 和 Mendeley LBC 数据集上测试了所提出方法的多功能性和性能以及损失函数的效率。在获得的实验结果中,表明所提出的空间注意模块和旋转不变性深度哈希网络在宫颈癌图像检索问题中产生了高性能。