Niu Kailin, Lyu Quanjun, Zhang Shuhua, Wang Chongjian, Mao Zhenxing, Cui Songyang, Gu Ruohua, Li Linlin
Department of Epidemiology and Health Statistics, College of Public Health, Zhengzhou University, Zhengzhou, Henan 450001, China.
Department of Nutrition, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, China.
Prim Care Diabetes. 2023 Apr;17(2):161-167. doi: 10.1016/j.pcd.2023.01.012. Epub 2023 Feb 2.
To explore the dose-response relationship of fruit and vegetable (F&V) intake and type 2 diabetes (T2D) risk in rural China.
A total of 38798 adults were recruited from the Henan Rural Cohort Study. F&V intake was assessed by a validated food-frequency questionnaire. Logistic regression and restricted cubic splines analysis were conducted to calculate the odds ratio (OR) for T2D relative to F&V intake and investigate the dose-response relationship.
Higher intake of fruit or combined F&V was in connection with a lower risk of T2D, after adjusting for multiple confounders. After analyzing the dose-response relationship, we found that the odds of T2D decreased significantly with fruit consumption ≥ 260 g/day or F&V intake between 600 and 1000 g/day. And in subgroup analysis, we found that the negative correlation between fruit consumption and T2D was more pronounced in non-current smokers and non-current drinkers.
High intake of fruit alone or combined F&V is related to a reduced risk of T2D in rural China. Fruit intake ≥ 260 g/day and total F&V consumption of 600-1000 g/day should be encouraged to promote good health.
探讨中国农村地区水果和蔬菜摄入量与2型糖尿病（T2D）风险之间的剂量反应关系。
从河南农村队列研究中招募了总共38798名成年人。通过经过验证的食物频率问卷评估水果和蔬菜摄入量。进行逻辑回归和受限立方样条分析，以计算T2D相对于水果和蔬菜摄入量的优势比（OR），并研究剂量反应关系。
在调整多个混杂因素后，较高的水果摄入量或水果和蔬菜的联合摄入量与较低的T2D风险相关。在分析剂量反应关系后，我们发现，当水果摄入量≥260克/天或水果和蔬菜摄入量在600至1000克/天之间时，T2D的发病几率显著降低。在亚组分析中，我们发现水果摄入量与T2D之间的负相关在非当前吸烟者和非当前饮酒者中更为明显。
在中国农村地区，单独高水果摄入量或水果和蔬菜的联合高摄入量与降低T2D风险相关。应鼓励每天摄入≥260克水果以及600 - 1000克的水果和蔬菜总量，以促进健康。
