Danish Cancer Society Research Center, Strandboulevarden 49, 2100, Copenhagen, Denmark.
Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark.
Eur J Nutr. 2023 Jun;62(4):1647-1656. doi: 10.1007/s00394-023-03100-4. Epub 2023 Feb 5.
This study assessed the validity of the Dietary Quality Score (DQS) and investigated the association between the DQS and risk factors for cardiometabolic diseases.
The DQS was calculated based on an updated 23-item FFQ and validated against a 376-item FFQ. A sub-sample of 450 men and women aged 18-73 years, from the Danish Diet, Cancer and Health-Next generations (DCH-NG) cohort, completed the updated 23-item FFQ. We investigated the associations between the DQS and risk factors for cardiometabolic diseases (lipids, haemoglobin A1c (HbA1c), high-sensitive C-reactive protein (hs-CRP), blood pressure (BP), waist circumference (WC), visceral and total fat mass) using linear regression models.
A high DQS, i.e. healthy dietary habits, was significantly associated with a higher intake of fruits, vegetables, fish, fibre, several vitamins and minerals and a lower intake of saturated fat. Moreover, a high DQS was significantly associated with lower levels of LDL cholesterol (P = 0.0133), Hs-CRP (P = 0.0449), WC (P = 0.0161), visceral fat (P = 0.0003), total fat mass (P = 0.0106) and total fat percentage (P = 0.0030) and significantly associated with a higher HDL cholesterol (P = 0.0379) level, when adjusting for education, smoking habits and physical activity. There was no association with total cholesterol, triglycerides, HbA1c, BP and BMI.
The DQS, based on the updated 23-item FFQ, is a valid tool to classify individuals into groups with low, average and high dietary quality in the Danish population. Furthermore, a high DQS is significantly associated with lower levels of several risk factors for cardiometabolic diseases.
本研究评估了膳食质量评分(DQS)的有效性,并探讨了 DQS 与心血管代谢疾病风险因素之间的关联。
根据更新的 23 项 FFQ 计算 DQS,并与 376 项 FFQ 进行验证。丹麦饮食、癌症和健康-下一代(DCH-NG)队列的 450 名 18-73 岁的男性和女性亚样本完成了更新的 23 项 FFQ。我们使用线性回归模型调查了 DQS 与心血管代谢疾病(血脂、糖化血红蛋白(HbA1c)、高敏 C 反应蛋白(hs-CRP)、血压(BP)、腰围(WC)、内脏和总脂肪量)风险因素之间的关联。
高 DQS,即健康的饮食习惯,与水果、蔬菜、鱼类、纤维、几种维生素和矿物质的摄入量较高以及饱和脂肪的摄入量较低显著相关。此外,高 DQS 与 LDL 胆固醇(P=0.0133)、Hs-CRP(P=0.0449)、WC(P=0.0161)、内脏脂肪(P=0.0003)、总脂肪量(P=0.0106)和总脂肪百分比(P=0.0030)水平较低显著相关,当调整教育、吸烟习惯和体力活动时,与 HDL 胆固醇(P=0.0379)水平较高显著相关。与总胆固醇、甘油三酯、HbA1c、BP 和 BMI 无关联。
基于更新的 23 项 FFQ 的 DQS 是一种有效的工具,可以将个体分为丹麦人群中低、中、高膳食质量组。此外,DQS 较高与心血管代谢疾病的几个风险因素水平较低显著相关。