Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing, China.
Global Center for Infectious Disease and Policy Research, Global Health and Infectious Diseases Group, Peking University, Beijing, China.
Int J Public Health. 2023 Jan 20;68:1605426. doi: 10.3389/ijph.2023.1605426. eCollection 2023.
We aimed to evaluate global epidemiological features of human monkeypox (mpox) cases and their associations with social-economic level and international travel arrivals. We estimated the pooled value by random-effects models. Then, we conducted an ecological study to evaluate the relationship of confirmed cases with social-economic indices and international travel arrivals using correlation analyses. The average age (2022: 35.52, 95% CI [28.09, 42.94] vs. before 2022: 18.38, 95% CI [14.74, 22.02]) and comorbidity rate (2022: 15.7%, 95% CI [8.9%, 22.4%] vs. before 2022: 14.9%, 95% CI [8.5%, 21.3%]) of mpox cases in the 2022 human mpox outbreak were significantly higher than those of cases before 2022. During the 2022 mpox outbreak, the proportion of men who have sex with men (MSM) was high (79.8%, 95% CI [65.5%, 94.2%]). The number of confirmed mpox cases in 2022 significantly correlated with high social-economic levels and international travel arrivals (all < 0.05). Our findings highlighted the importance of early surveillance and timely detection in high-risk populations, including older people, MSM, and travelers, which is crucial to curb the wide transmission of mpox.
我们旨在评估人类猴痘（mpox）病例的全球流行病学特征及其与社会经济水平和国际旅行入境的关联。我们采用随机效应模型估计汇总值。然后，我们进行了一项生态研究，通过相关分析评估确诊病例与社会经济指数和国际旅行入境的关系。2022 年的平均年龄（2022 年：35.52，95%置信区间[28.09，42.94]与 2022 年前：18.38，95%置信区间[14.74，22.02]）和合并症发生率（2022 年：15.7%，95%置信区间[8.9%，22.4%]与 2022 年前：14.9%，95%置信区间[8.5%，21.3%]）在 2022 年人类猴痘疫情中显著高于 2022 年前。在 2022 年猴痘疫情中，男男性行为者（MSM）的比例较高（79.8%，95%置信区间[65.5%，94.2%]）。2022 年确诊的猴痘病例数与高社会经济水平和国际旅行入境显著相关（均<0.05）。我们的研究结果强调了在高危人群中进行早期监测和及时发现的重要性，包括老年人、MSM 和旅行者，这对于遏制猴痘的广泛传播至关重要。
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