Bodaghi Ali, Fattahi Nadia, Ramazani Ali
Department of Chemistry, Tuyserkan Branch, Islamic Azad University, Tuyserkan, Iran.
Department of Chemistry, University of Zanjan, Zanjan, 45371-38791, Iran.
Heliyon. 2023 Feb;9(2):e13323. doi: 10.1016/j.heliyon.2023.e13323. Epub 2023 Jan 30.
The use of biomarkers as early warning systems in the evaluation of disease risk has increased markedly in the last decade. Biomarkers are indicators of typical biological processes, pathogenic processes, or pharmacological reactions to therapy. The application and identification of biomarkers in the medical and clinical fields have an enormous impact on society. In this review, we discuss the history, various definitions, classifications, characteristics, and discovery of biomarkers. Furthermore, the potential application of biomarkers in the diagnosis, prognosis, and treatment of various diseases over the last decade are reviewed. The present review aims to inspire readers to explore new avenues in biomarker research and development.
在过去十年中，生物标志物作为疾病风险评估中的早期预警系统的应用显著增加。生物标志物是典型生物过程、致病过程或对治疗的药理反应的指标。生物标志物在医学和临床领域的应用与鉴定对社会有着巨大影响。在本综述中，我们讨论了生物标志物的历史、各种定义、分类、特征及发现。此外，还综述了过去十年生物标志物在各种疾病的诊断、预后及治疗中的潜在应用。本综述旨在激发读者探索生物标志物研发的新途径。
