Department of Biostatistics and Medical Informatics, Faculty of Medicine, Erzincan Binali Yıldırım University, 24000 Erzincan, Turkey.
Institute of Physics and Technology, Petrozavodsk State University, 33 Lenin Str., 185910 Petrozavodsk, Russia.
Sensors (Basel). 2022 Jun 25;22(13):4820. doi: 10.3390/s22134820.
Since February 2020, the world has been engaged in an intense struggle with the COVID-19 disease, and health systems have come under tragic pressure as the disease turned into a pandemic. The aim of this study is to obtain the most effective routine blood values (RBV) in the diagnosis and prognosis of COVID-19 using a backward feature elimination algorithm for the LogNNet reservoir neural network. The first dataset in the study consists of a total of 5296 patients with the same number of negative and positive COVID-19 tests. The LogNNet-model achieved the accuracy rate of 99.5% in the diagnosis of the disease with 46 features and the accuracy of 99.17% with only mean corpuscular hemoglobin concentration, mean corpuscular hemoglobin, and activated partial prothrombin time. The second dataset consists of a total of 3899 patients with a diagnosis of COVID-19 who were treated in hospital, of which 203 were severe patients and 3696 were mild patients. The model reached the accuracy rate of 94.4% in determining the prognosis of the disease with 48 features and the accuracy of 82.7% with only erythrocyte sedimentation rate, neutrophil count, and C reactive protein features. Our method will reduce the negative pressures on the health sector and help doctors to understand the pathogenesis of COVID-19 using the key features. The method is promising to create mobile health monitoring systems in the Internet of Things.
自 2020 年 2 月以来,世界一直在与 COVID-19 疾病进行激烈的斗争,随着该疾病演变为大流行,卫生系统承受了巨大的压力。本研究的目的是使用 LogNNet 储层神经网络的后向特征消除算法,获得 COVID-19 诊断和预后最有效的常规血液值(RBV)。该研究的第一个数据集共有 5296 名患者,其中 COVID-19 检测的阴性和阳性患者数量相同。LogNNet 模型在使用 46 个特征对疾病进行诊断时达到了 99.5%的准确率,仅使用平均红细胞血红蛋白浓度、平均红细胞血红蛋白和活化部分凝血酶原时间的准确率为 99.17%。第二个数据集共有 3899 名在医院接受 COVID-19 治疗的患者,其中 203 名是重症患者,3696 名是轻症患者。该模型在使用 48 个特征确定疾病预后时达到了 94.4%的准确率,仅使用红细胞沉降率、中性粒细胞计数和 C 反应蛋白特征的准确率为 82.7%。我们的方法将减轻卫生部门的压力,并帮助医生使用关键特征了解 COVID-19 的发病机制。该方法有望在物联网中创建移动健康监测系统。